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The Single Cell Application Module within PerkinElmer’s Syngistix^™ for ICP-MS software is the ideal tool for laboratories analyzing metal content in cells, either from bioaccumulation of metals or metallic nanoparticles in solution or measuring the intrinsic metal content of the cell. This unique combination of hardware and software module allows the differentiation and quantification between the media and cellular fractions of the same analyte. In a single analysis, cell metal or particulate content, cell-containing metal concentration, mass per cell and mass distribution can all be determined without the need for subsequent data processing. Coupled with the NexION^® series ICP-MS, the Syngistix Single Cell Application Module is the world’s first single cell ICP-MS dedicated software, delivering speed, flexibility, automation and ease-of-use.