Ideal for analyzing food, cannabis, and environmental samples, our robust and reliable QSight® triple quad systems consistently deliver the throughput and productivity you need in your analytical testing lab. Now we’ve added the premier model to our QSight family: the high performance 400 series. This ready-to-implement solution has the highest sensitivity and throughput the industry has ever seen and the capability to test for the most challenging, complex samples, including cannabis.
Please enter valid quantity
Please log in to add favorites.
NULL OR EMPTY CART
Future proof your lab with the flagship QSight triple quad 400 series. This powerful LC/MS/MS system is engineered to deliver exponentially better sensitivity that commercial testing labs, global food manufacturers and exporters, and highly regulated cannabis labs need to meet their most stringent requirements – today and tomorrow.
|Model Name||QSight 400 Series|
Owing to the toxicity of heavy metals, it is increasingly important to test cannabis flowers and other cannabis derivatives so that patient and consumer safety is maintained as the use of cannabis becomes more common. This need has translated into an increasing demand for testing cannabis flowers and other cannabis derivatives for toxins such as the heavy metals cadmium (Cd), lead (Pb), arsenic (As), and mercury (Hg). In this application note, we present data to illustrate the successful validation of the Titan MPS™ Microwave Sample Preparation System and the NexION® ICP-MS for the determination of heavy metals in cannabis flower according to the validation protocols set in USP General Chapter <233>, which are commonly used for evaluation of the levels of elemental impurities in samples.
Multiclass, multiresidue method for analysis of 73 veterinary drugs (covering 13 different chemical classes) in chicken samples by coupling solvent extraction method with LC/MS/MS. Better recoveries were obtained for all the analytes without sample clean-up when comparing with different sample cleanup methods. Due to the high sensitivity of QSight mass spectrometer and its unique StayClean technology (hot-surface induced desolvation (HSID) and Laminar Flow Ion Guide),20 sample extracts can be analyzed directly without timeconsuming solvent evaporation and analyte concentration steps.
A New, Sensitive Method for Lignan Metabolite Detection of Flaxseed-Fed Mice Using LC/MS/MS
Per- and polyfluoroalkyl substances (PFASs), or Per- and polyfluorinated compounds (PFCs), represent a group of anthropogenic chemicals that have been produced and widely used in industrial applications and consumer products since the 1950s. The unique physical and chemical characteristics of these compounds (highly stable and resistant to degradation), along with their ubiquitous use, have led to the accumulation of PFAS in the environment, with growing concern of human exposure to these chemicals. The most widely used analytical method for PFAS monitoring is LC/MS/MS owing to its high sensitivity, selectivity and robustness. Recently, with the advancement and availability of highly sensitive mass spectrometers, a trend towards developing a high throughput analytical method for monitoring PFASs by direct injection without SPE has been appreciated. The direct injection approach can achieve higher levels of sample throughput, and reduce potential analyte loss and contamination caused by SPE sample preparation, as demonstrated by this study using PerkinElmer’s QSight® 420 mass spectrometer, coupled with UHPLC for the determination of trace amount of PFOA and PFOS in drinking and surface water samples.
Following the 2018 legalization of recreational cannabis usage in Canada, the quality and safety of cannabis products has garnered significant attention. Health Canada has developed a regulatory program mandating pesticide testing on all cannabis products. Under the program, licensed producers (LPs) of cannabis products in Canada are required to send representative samples of products to independent laboratories for pesticide screening and quantification.
In this application note, a robust and reliable method for the analysis of 96 pesticides in cannabis flower by LC/MS/MS utilizing both ESI and APCI modes is presented. The method not only offers ultra-low detection limits at or below the Health Canada regulatory levels, but also offers significant efficiency gains over other available methodologies. Utilizing LC/MS/MS with both ESI and APCI modes obviates the need to perform both GC/MS/MS and LC/MS/MS analyses to analyze all 96 regulated pesticides, saving significant time and money for operators.
Dry pet food is produced with grains and cereal by-products rejected for human consumption.
Several directives throughout the EU provide guidance on environmental quality standards for water, and define more than 30 priority substances as significant risk to humans. Many of the monitoring limits within these directives are set at low µg/L (ppb) levels, and as such, require highly sensitive methods and instrumentation.
In this study, various methods for the separation, detection and quantitation of complex polar contaminants by UHPLC/MS/MS are presented. Utilizing two columns and three separate analytical methods, metabolites such as trifluoracetic acid, the antidiabetic metformin, and various inorganic contaminants, such as chlorate and bromate are successfully and efficiently quantified.
Haloacetic acids (HAAs) are a class of undesired by-products resulting from the reaction of chlorinated disinfectants with natural organic matter in water. The resulting substances are considered major disinfection by-products (DBP), which are known for being carcinogenic and also associated with reproductive problems in humans. The five major HAAs of particular concern include monochloroacetic acid (MCAA), monobromoacetic acid (MBAA), dichloroacetic acid (DCAA), dibromoacetic acid (DBAA) and trichloroacetic acid (TCAA). Haloacetic acids are regulated by the U.S. Environmental Protection Agency (EPA) government. In this application note, a reliable and fast method for determination and quantification of five HAAs in potable drinking water is presented using a PerkinElmer QSight® LX50 UHPLC system coupled to a PerkinElmer QSight 220 MS/MS detector. The five HAAs eluted within three minutes with excellent reproducibility.
Estrogens play an important role in human breast carcinogenesis and are of clinical importance. Currently, the most widely used techniques are automated immunoassays, owing to the fast sample throughput and minimal sample preparation required. However, these techniques suffer from poor accuracy and precision at low concentration levels, and are susceptible to interferences. The objective of this study was to develop a highly sensitive method for the analysis of estrogens in serum, without derivatization, using the QSight® 420 LC/MS/MS system.
Liquid chromatography tandem mass spectrometry (LC/MS/MS) has become the method of choice for pesticide analysis due to its high selectivity and sensitivity as well as its suitability for a wide range of compounds in various sample matrices. 0 In this study, a fast, sensitive and selective multi- residue method has been developed for analysis of over 200 pesticides in rice samples by coupling a modified QuEChERS extraction method with LC/MS/MS. Using time-managed- MRM in the QSight triple quadrupole mass spectrometer, the optimum dwell time of multiple MRM transitions can be generated automatically for the targeted analytes. This not only saves time in method development but also improves data quality and analytical performance, as demonstrated in this study by the results of multi- residue pesticide analysis in rice samples.
Liquid chromatography-tandem mass spectrometry (LC/MS/MS) has become the method of choice for pesticide The state of Oregon has issued regulatory limits for 59 pesticide residues in both cannabis flower and concentrates. In this study, all 59 pesticides were spiked into cannabis flower samples and analyzed by coupling QuEChERS sample preparation with LC/MS/MS. All the 59 pesticides in Oregon’s regulated list were detected using this methodology, with results well below the current action limits specified. Recoveries of pesticides from spiked cannabis flower extracts are shown to be between 70-120%.
A selective and sensitive LC/MS/MS method for fast identification and analysis of meat samples using three peptides specific for pork as biomarkers. . The optimized sample preparation procedure is easy to follow and can be used for analyzing raw, cooked and processed meat products. This method can selectively detect peptides from pork meat species at a threshold detection limit of 1% w/w (10 mg/g) in a variety of food products and thus the method can be useful for analysis of Halal food (or pork related food products) samples.
This work pursued an effective, efficient and robust HPLC method for the quantitative analysis of lactic and acetic acid in beers by HPLC with PDA detection.
A recent recall of contaminated eggs in Europe has generated a serious health concern for fipronil poisoning. Fipronil is a highly toxic insecticide and it is used to protect crops. The U.S. EPA has classified fipronil as a group C carcinogen. In this study, we describe a fast and robust analytical method for identifying fipronil and its metabolites with the PerkinElmer QSight 200 series LC/MS/MS triple quadrupole instrument. The results demonstrate excellent recovery, linearity and reproducibility and superior sensitivity for this method. The three-step sample preparation procedure is quick and easy, and the LC/MS/MS analysis time can be carried out within six minutes with great separation for all analytes.
Determination, Confirmation and Quantitation of Multi-Class Antibiotic Residues in Milk by UHPLC MS/
In apiculture, sulfonamides are the most commonly used antibiotics to treat American and European Foulbrood, a type of disease that infects bees. This application note demonstrates how QSight 200 System can provides a very sensitive and robust platform for the analysis of sulfonamides in honey.
In this work, we present a fast and sensitive LC/MS/MS method
Glyphosate (N-(phosphonomethyl) glycine), an organophosphorus compound, is used to kill weeds (e.g. annual broadleaf weeds and grasses) that compete with crops. Like other pesticides, glyphosate is directly administered to food products and can come in contact with both food workers and the environment, resulting in the bio burden of exposure in uncontrolled regional populations. Our study reports a 12 minute LC/MS/MS method with an amino-based column to analyze glyphosate and other related polar compounds in underivatized states, with exceptional selectivity and sensitivity.
For sunflower seed processors and feed manufacturers alike, rapid and accurate quality control of sunflower seed meal is important ot ensure nutritional specification on the meal is correct.
Estrogen plays an important role in the human body, but excess concentrations of endogenous estrogens, a known endocrine disrupting compound (EDC), in urine have been linked to the development and growth of breast cancer and tumors in females. Endogenous estrogens, including estrone (E1), 17ß-estradiol (E2), and estriol (E3), have also been detected in environmental matrices such as surface, waste and drinking water, even after extensive removal treatments. The accurate and efficient quantification of estrogen in both urine and water is paramount to ensuring the health of humans and animals in impacted ecosystems.
This application note details a method for the analysis of three endogenous estrogens at low ng/L (ppt) levels in both urine and water matrices. The method presented utilizes a PerkinElmer QSight® 420 triple quadrupole LC/MS/MS, and demonstrates good linearity, precision and accuracy, without the need for derivatization and concentration with SPE.
Following the 2018 legalization of recreational cannabis usage in Canada, the quality and safety of cannabis products has garnered significant attention. Health Canada has developed a regulatory program mandating pesticide testing on all cannabis products. Under the program, licensed producers (LPs) of cannabis products in Canada are required to send representative samples of products to independent laboratories for pesticide screening and quantification.In this application note, a robust and reliable method for the analysis of 96 pesticides in cannabis flower by LC/MS/MS utilizing both ESI and APCI modes is presented. The method not only offers ultra-low detection limits at or below the Health Canada regulatory levels, but also offers significant efficiency gains over other available methodologies. Utilizing LC/MS/MS with both ESI and APCI modes obviates the need to perform both GC/MS/MS and LC/MS/MS analyses to analyze all 96 regulated pesticides, saving significant time and money for operators.
EU water policies are reevaluated on a consistent basis to ensure water sources do not contain contaminants at levels above regulatory levels. As regulations are reviewed, regulatory limits are often lowered, and analytical techniques must adapt to meet the new stringent requirements.
In this application note, an LC/MS/MS method for the determination of 214 regulated contaminants is presented. The direct injection method, utilizing a PerkinElmer® QSight 420, is optimized with the use of dual ionization sources (APCI and ESI). Additionally, an inter-laboratory study is detailed to illustrate the method transferability between instruments, utilizing the compound Atrazine.
Beta-adrenergic receptor agonists (ß- agonists) are synthetic drugs utilized in the treatment of conditions such as asthma in humans, and are also used as a growth-promoting agent in food-producing animals. The use of ß- agonists in food-producing livestock has been either banned or regulated across many countries owing to human health concerns.
To aid in the monitoring and detection of ß- agonists in livestock, a highly sensitive and selective analytical method has been developed, and is presented in this study. This LC/MS/MS method details the analysis of 13 ß- agonists in pork samples, and utilizes isotopically-labeled internal standards to compensate for matrix effects present in complex food matrices.
This Application Note talks about pesticide residues analysis tested by Clarus 690 Gas Chromatograph
DA 7250 NIR technology is suitable for soybean producers to understand the value of the soybean they purchase by testing compostion such as oil and protein and helps seed breeders by identifying the fatty acid profiles.
Today’s plastics are some of the most used materials on a global volume basis. Broadly integrated into today’s industrial and commercial lifestyles, they make a major, irreplaceable contribution to virtually every product category.
In this compendium you will find a wide range of applications for polymers, plastics, rubbers and advanced materials. Discover how to put these applications to work for you simply and efficiently.
Per- and polyfluoroalkyl substances (PFAS) are a diverse group of synthetic organic compounds which have been utilized as aqueous film forming foams (AFFF) for firefighting purposes, and as stain and water resistant coatings on a number of consumer products such as clothing, furniture or cookware. PFAS compounds are highly stable from a chemical and physical standpoint, and their resistance to degradation in the environment has led to concerns over accumulating levels of PFAS in environmental habitats.
In this application note, a versatile and efficient direct inject approach to the analysis of 17 PFAS compounds in drinking and surface water samples utilizing a PerkinElmer QSight® 420 LC/MS/MS is presented. The method offers improved sample throughput, while reducing the potential of analyte loss and contamination that can result from SPE sample preparation.
This application note presents a sensitive and reliable LC/MS/MS method using the PerkinElmer QSight
A simple and sensitive method for the simultaneous determination of plant growth regulators
Learn more about our various testing methods and applications for cannabis analyses by reading through our Cannabis Testing brochure.
The grain industry is very complex. It’s global, diverse, and can also present analytical challenges. Today’s grain users demand more when it comes to quality, safety, and uniformity. In addition, they seek diverse products with unique characteristics.
PerkinElmer is equipped to help the grain industry in its quest to feed the world – nutritiously and economically. Our testing and analysis solutions encompass the three primary areas required for complete knowledge of grains and their derivatives – composition, functionality, and safety.
Pesticides can adversely affect human health through the food we consume but can also leach into soil and groundwater and impact us through the environment. To keep up with a complex and constantly changing regulatory environment, your pesticide analysis solution needs to keep up with your burgeoning sample load.
Our QSight triple quad LC/MS/MS family has always been known for its robust and reliable performance. But now there’s something new – something better: the high performance 400 series. Our ready-to-implement solution has the highest sensitivity and throughput the industry has ever seen and the capability to test for the most challenging samples and analytes.
Our QSight triple quad LC/MS/MS family has always been known for its robust and reliable performance. But now there’s something new – something better: the high performance 400 series.
The Polymer Market consists of a huge diversity of manufacturers of industrial products running many different processes yet still facing similar challenges. There is more and more pressure to achieve high product quality and reduce costs in order to stay one step ahead of the competition.
Our modular Simplicity 3Q™ software is ideal for acquiring, quantifying and reporting
Lab reequirements for QSight triple quad LC/MS/MS systems, including storage, suppleis, space, electrical, power, gas supply requirements
Ion Transmission Through a Quadrupole Ion Guide Under the Combined Influence of Viscous Flow and RF
Theoretical Studies of Swirling Flow and Heating Methods on Droplet Evaporation in a Heated Coaxial