ProSense® 680 is a protease activatable fluorescent in vivo imaging agent that is activated by key disease associated proteases such as Cathepsin B, L, S and Plasmin. ProSense 680 is optically silent in its unactivated state and becomes highly fluorescent following protease-mediated activation.
ProSense 680 can be used as a marker for disease progression and therapeutic response in animal models of arthritis. This agent can also be used as a marker for disease progression in animal tumor models.
Disclaimer: For laboratory use only. This product is intended for animal research only and not for use in humans.
|Fluorescent Agent Type||Activatable|
|Optical Imaging Classification||Fluorescence Imaging|
|Product Brand Name||ProSense|
|Quantity in a Package Amount||1.0 Units|
|Shipping Condition||Blue Ice|
|Therapeutic Area||Atherosclerosis, Arthritis, Inflammation, Oncology/Cancer|
|Unit Size||1 Vial (10 doses)|
|Wave Length||680 nm|
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|Resource Type||File Name||File Format|
|Brochure||FMT Fluorescence Tomography in vivo Imaging Systems||PDF 1 MB|
|Brochure||In Vivo Imaging Agents Brochure||PDF 2 MB|
|Application Note||In Vivo Imaging of Atherosclerosis Disease Using FMT||PDF 1 MB|
|Application Note||Noninvasive In Vivo Quantitation of Asthma Severity Using FMT||PDF 488 KB|
|Technical Note||ProSense 680 (Protocol)||PDF 256 KB|
|Technical Note||ProSense® 680 (Data Sheet)||PDF 47 KB|
|Poster||Non-Invasive Near-Infrared Fluorescence Quantitative Tomography (FMT™) of the Effects of PDE4 Inhibitor Therapy in an LPS Murine Model of COPD In Vivo||PDF 448 KB|
|Poster||Non-Invasive Quantitative Tomography of Disease Progression and Therapeutic Response||PDF 581 KB|
|Citations Library||View peer reviewed publications using PerkinElmer's In Vivo Imaging Reagents||Link|
|Webinars||View our complete list of in vivo webinars available on demand||Link|