N-Methyl-4-phenylpyridinium (MPP+) acetate, tritiated on the methyl group. MPP+ is a substrate for the organic cation ion transporter (OCT), the dopamine transporter (DAT), the norepinephrine transporter (NET), and the serotonin transporter (SERT).
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NULL OR EMPTY CART
|Part Number||Unit Size||List Price||Your Price||Quantity|
|NET914050UC||50 µCi||512.00 USD|
|NET914250UC||250 µCi||1363.00 USD|
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MPP+ is a dopaminergic selective neurotoxin, and has been used to study Parkinson's disease.
We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.
Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NET914:
|Concentration||1.0 - 10 mCi/mL|
|Label Position||Specifically Labeled|
|Product Brand Name||NEN Radiochemicals|
|Receptor Type||Dopamine Transporter|
|Shipping Condition||Dry Ice|
|Special Ordering Information||This is a radioactive product - shipping address must have a license to receive radioactive materials.|
|Therapeutic Area||CNS & Neurologic|
|Unit Size||50 µCi|