L-kynurenine (KYN), labeled with tritium on the phenyl group. 3H-KYN is commonly used in amino acid receptor studies and kynurenine metabolic studies in the brain.
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L-Kynurenine is a metabolite of the L-tryptophan degradation pathway and participates in niacin production. Kynurenine-3-monooxygenase which converts L-Kynurenine to L-3-hydroxykynurenine is being studied for its role in neuronal damage and mental disorders such as depression and schizophrenia. Inhibition of L-Kynurenine production is also being considered as a promising approach to anticancer therapy.Immunosuppressant research ios also being done as it suppresses allogeneic T-cell proliferation.
|Label Position||Specifically Labeled|
|Product Brand Name||NEN Radiochemicals|
|Shipping Condition||Blue Ice|
|Special Ordering Information||This is a radioactive product - shipping address must have a license to receive radioactive materials.|
|Unit Size||50 µCi|
Since 1985, the unique NENSure system has set the standard for radiochemical packaging. Based on proven performance over millions of shipments, the system provides: Ease of use, Safe storage of unused product and Reduced radiation exposure. Many NEN brand research products, including 32P-, 33P-, 35S-, 3H-, 14C- and 125I-labeled compounds, are packaged in the NENSure System, as are most radionuclides.