Positron emission tomography can be used to visualize antibodies and other biologics non-invasively, in vivo. I-124 is offered for molecular imaging using immuno-positron emission tomography (immuno-PET) or Cerenkov luminescence imaging (CLI) techniques. Immuno-PET with I-124 radionuclide enables noninvasive imaging of whole, intact antibodies.
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Iodine-124 (124I) is a positron-emitting non-residualizing radionuclide with a relatively long-lived half-life suited for immuno-PET studies. 124I-labeled monoclonal antibodies (mAbs) are currently being used for clinical immuno-PET. 124I is the radionuclide of choice in combination with non-internalizing mAbs. A major advantage of 124I is that the radioiodination of proteins is a common practice within radiochemistry labs.
For research and investigational use only.
*Zirconium-89 and Iodine-124 provided by PerkinElmer are for research and investigational use only and not for use in humans. Only the research content of the white paper is relevant to the PerkinElmer products. PerkinElmer makes no clinical use representations for Zirconium-89 and Iodine-124.
| Detection Method | Radiometric |
|---|---|
| Product Brand Name | NEN Radiochemicals |
| Quantity in a Package Amount | 1.0 per pack |
| Radioisotope | I-124 |
| Radionuclide | 124I |
| Shipping Condition | Ambient |
| Special Ordering Information | This is a radioactive product - shipping address must have a license to receive radioactive materials. |
| Unit Size | mCi |
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