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Epibatidine, ([125I]-IPH), [125I]-, 50µCi

Epibatidine, labeled with 125I. Epibatidine has analgesic activities, has been shown to function as an agonist at nicotinic acetylcholine receptors, and has been shown to bind muscarinic and serotonin 5-HT3 receptors.

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Part Number Unit Size List Price Your Price Quantity
NEX358010UC 10 µCi 1818.00 USD
NEX358050UC 50 µCi 3985.00 USD
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We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX358:

  1. Garza, A., Huang, L.Z., Son, J.H., Winzer-Serhan, U.H. (2009), Expression of nicotinic acetylcholine receptors and subunit messenger RNAs in the enteric nervous system of the neonatal rat. Neuroscience, 158 (4): 1521-1529.
  2. Huang, L.Z., Winzer-Serhan, U.H. (2006), Effects of paraformaldehyde fixation on nicotinic acetylcholine receptor binding in adult and developing rat brain sections. J Neurosci Methods, 153 (2): 312-317.


Detection Method Radiometric
Fresh Lot Days First Monday of even Months
Label Position Nominally Labeled
Molecular Weight 298.0
Product Brand Name NEN Radiolabeled Ligands
Radioisotope I-125
Radionuclide 125I
Receptor Type Nicotinic
Shipping Condition Dry Ice
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area CNS & Neurologic, Pain, Inflammation
Unit Size 50 µCi

Resources, Events & More

Resource Type File Name File Format
Technical Note Low Volume Handling Suggestions for Iodine-125 Labeled Compounds PDF  177 KB
Flyer Using the NENSure Packaging System from PerkinElmer PDF  447 KB