Cytisine HCl, [3,5-3H(N)]- will have fresh lot dates on the second Monday in April and October.
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Cytisine is a partial agonist of nicotinic acetylcholine receptors. These receptors are responsible for motor nerve-muscle communication, and are involved in the peripheral and central nervous system. The are potential drug targets for depression, cognitive disorders, pain, epilepsy, smoking cessation, anxiety, and neurodegenerative diseases.
We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.
Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NET1054:
|Fresh Lot Days||Second Monday in April and October|
|Label Position||Nominally Labeled|
|Product Brand Name||NEN Radiochemicals|
|Shipping Condition||Dry Ice|
|Special Ordering Information||This is a radioactive product - shipping address must have a license to receive radioactive materials.|
|Therapeutic Area||CNS & Neurologic, Pain, Inflammation|
|Unit Size||250 µCi|