50 µCi quantities of [14C]-Citric acid are available for your research.
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ATP citrate lyase (ACL) is a cytosolic enzyme that catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a necessary cofactor. The ACL-dependent synthesis of acetyl-CoA is thought to be an essential step for the de novo synthesis of fatty acids and cholesterol. For this reason, inhibition of ACL has been pursued as a strategy to treat dyslipidemia and obesity.
| Concentration | 0.05 mCi/mL |
|---|---|
| Detection Method | Radiometric |
| Label Position | Specifically Labeled |
| Molecular Weight | 192.12 |
| Product Brand Name | NEN Radiochemicals |
| Radioisotope | C-14 |
| Radionuclide | 14C |
| Shipping Condition | Blue Ice |
| Special Ordering Information | This is a radioactive product - shipping address must have a license to receive radioactive materials. |
| Unit Size | 50 µCi |
