Annexin A5 (Annexin V) is a cellular protein in the annexin group. Annexin V is a probe commonly used to detect apoptotic cells by its ability to bind to phosphatidylserine, a marker of apoptosis when it is on the outer leaflet of the plasma membrane.
Annexin-Vivo™ 750, from PerkinElmer, is a targeted fluorescent imaging agent comprising this selective protein, Annexin A5 and a near-infrared (NIR) fluorochrome. This agent has been developed to enable in vivo visualization and quantification of the membrane-bound phospholipid, phosphotidylserine, exposed in the outer leaflet of the cell membrane lipid bilayer during the early stages of apoptosis.
Disclaimer: For laboratory use only. This product is intended for animal research only and not for use in humans.
|Fluorescent Agent Type||Targeted|
|Optical Imaging Classification||Fluorescence Imaging|
|Quantity in a Package Amount||1.0 Units|
|Shipping Condition||Blue Ice|
|Therapeutic Area||Atherosclerosis, Oncology/Cancer|
|Unit Size||1 Vial (10 doses)|
|Wave Length||750 nm|
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|Resource Type||File Name||File Format|
|Brochure||FMT Fluorescence Tomography in vivo Imaging Systems||PDF 1 MB|
|Brochure||In Vivo Imaging Agents Brochure||PDF 2 MB|
|Application Note||Imaging Hepatocellular Liver Injury using NIR-labeled Annexin V||PDF 3 MB|
|Technical Note||Annexin-Vivo 750 (Protocol)||PDF 257 KB|
|Technical Note||Annexin-Vivo™ 750 (Data Sheet)||PDF 158 KB|
|Poster||Combined efficacy & toxicity imaging following acute 5-FU treatment of HT-29 tumor xenografts||PDF 1 MB|
|Poster||Fluorescence tomographic imaging of efficacy & toxicity following acute 5-FU treatment of HT29 cells||PDF 2 MB|
|Citations Library||View peer reviewed publications using PerkinElmer's In Vivo Imaging Reagents||Link|
|Webinars||View our complete list of in vivo webinars available on demand||Link|
|Webinars||In vivo imaging of drug-induced liver injury using NIR fluorescent imaging agents - View On Demand||Link|