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The Alliance HIV-1 p24 Antigen ELISA is for the detection of HIV-1 and HIV-0 Subtypes in human serum, plasma and cell culture supernates. This kit provides reagents for immune complex disruption (ICD) of antigen/antibody complexes in serum and plasma samples and proprietary antibodies increasing the sensitivity of the assay. The ELAST p24 ELISA Amplification System also improves the sensitivity of Alliance HIV1 p24 ELISA kits by approximately 25-fold while extending the dynamic range of the assay. This kit is intended for research purposes only and is not approved for diagnostic use.