Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
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This product contains living cells. Some of our cAMPZen™ FroZen Cells may be restricted for sale in specified countries. Please inquire at your local sales office for more information.
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Frozen Cells validated for cAMP testing: Adrenergic a2A receptor, human recombinant, in CHO-K1 host cell. We provide one vial of frozen cells (2.5 million cells/vial). Some of our Frozen cells may be restricted for sale in specified countries. Please inquire at your local sales office for more information. You are authorized to utilize these frozen cell preparations one time only. Any attempt to transfer, re-use, or propagate these cells is expressly unauthorized and a violation of the product terms and conditions of sale.
|Assay Target Class||GPCR|
|Assay Target Type||Cell line|
|Assay Validated||cAMP, Downstream Phosphorylation|
|G-Alpha Natural Receptor||Gi/Go|
|Product Brand Name||cAMPZen|
|Second Messenger Release||cAMP, GTP exchange|
|Shipping Condition||Dry Ice|
|Therapeutic Area||Cardiovascular, Inflammation, Metabolic, Diabetes, Gastrointestinal|
|Unit Size||2.5 million cells|
PerkinElmer’s validated, ready-to-use AequoZen™or cAMPZen™ frozen, irradiated cells make it easier for you to perform functional testing of GPCRs. Just thaw and use! Reliable, convenient AequoZen cells for aequorin calcium testing or cAMPZen cells for cAMP testing let you get the testing done. So you can concentrate on results.
FroZen, -irradiated cells, are a well established product, that can be ordered as a consumable, and readily used to perform Aequorin functional assays (AequoZen) or cAMP assays (cAMPZen). While, for the G s–coupled receptors, an increase of cAMP is detected in such an assay, for G i-coupled receptors an inhibition of the forskolin-stimulated level of, cAMP is detected.