S-adenosylmethionine (SAM), labeled with C-14 on the methyl group. 14-SAM is commonly used in epigenetic assays.
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Application of [14C]SAM can be found in: methylation in epigenetics, a new caffeine biosynthetic pathway in tea leaves in phytochemistry, effect of salt stress on the metabolism of ethanolamine and choline in mangrove leaves in phytochemisty, pharmacokinetic of the orally administered salt in rats, etc.
|Label Position||Specifically Labeled|
|Product Brand Name||NEN Radiochemicals|
|Shipping Condition||Dry Ice|
|Special Ordering Information||This is a radioactive product - shipping address must have a license to receive radioactive materials.|
|Unit Size||50 µCi|
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This document contains general information designed to provide a basic understanding of radiation safety. While we believe the information to be accurate, regulatory requirements may change and information contained herein is not tailored to individual needs.
The use of substances labeled with carbon-14 has been extraordinarily valuable in many aspects of the life sciences for over half a century. One of the most versatile and simple ways to install carbon-14 in many compounds of interest is by methylating available heteroatoms like nitrogen, oxygen and sulfur to afford corresponding methyl-14C analogues.