Our LANCE® and LANCE® Ultra TR-FRET technologies provide a simple, highly-sensitive, and highly-reproducible platform for detection, quantitation and screening in microplate format. From biomarker detection assays, to cAMP/GPCR studies, to kinase and epigenetic assays, LANCE provides a flexible platform for many applications.
Time-resolved measurement for clearer signal resolution
Homogeneous (no wash steps, no separation steps)
Long signal stability
Highly reproducible result
LANCE europium chelates have been optimized for assay performance, signal level, energy transfer efficiency, background and sensitivity of the assay to interferences. The results are a superior S:B ratio and a very sensitive TR-FRET assay. You use less label and get more efficient use of assay reagents.
Our small (<800 Da) ULight acceptor dye decreases steric hindrance while maximizing signal for labeled substrates. The SureLight® APC acceptor dye provides a broad, antenna-like structure to help align fluorophores for optimal TR-FRET signal, making it excellent for measuring large binding interactions.
This product is designed to be used in combination with LANCE Ultra TR-FRET biomarker detection kits. The Ultra HiBlock buffer was specially developed buffer to block non-specific protein binding sites.