PerkinElmer

Receptor Ligand Binding

OF

A receptor ligand binding assay allows for the study and simple imaging of cell surface receptors for research and diagnostic applications. Receptor ligand binding is used in drug development applications to identify blocking antibodies or inhibitors that can modulate downstream signaling events, and is often used to screen for drugs that target hormone and neurotransmitter activity. We offer a range of tools for receptor ligand binding assays including radioligands, receptor-transfected cell membranes, and cell lines. Products available support both agonist and antagonist assays.

Our offerings include assays for:

  • Tyrosine kinase receptors
  • G-protein coupled receptors (GPCR)
  • Drug discovery and development
  • Ion channels
  • Protein analysis, detection, and interaction

Our collection of receptor ligand binding related assays includes fluorescence, LANCE® and DELFIA® time-resolved fluorescence, Alpha chemiluminescent assays, lites luminescence assays, and radiometric detection methods. Simplify the development of your assays and the calculation of your results using our radioligands, receptor-transfected cell membranes, and cell lines for receptor ligand binding applications.

Products & Services (541)
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Product Type
  • Consumables (2)
  • Instruments (7)
  • Reagents (532)
Target Species
  • Human (10)
Application
  • cAMP (26)
  • Drug Discovery & Development (332)
  • Mobility Shift (36)
  • Protein Analysis & Detection (5)
  • Protein-protein interactions (4)
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Sterile
  • No (4)
Therapeutic Area
  • Angiogenesis (27)
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Product Brand Name
  • AequoScreen (4)
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Material
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Detection Method
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Receptor Type
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Assay Validated
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Sample Type
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Radioisotope
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Radionuclide
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Fluorophore
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Label Position
  • Generally Labeled (6)
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Assay Points (200-50,000)
  • 500 (2)
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Assay Target Class
  • GPCR (187)
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  • Transporter (6)
  • Tyrosine Kinase Receptor (1)
Automation Compatible
  • No (20)
  • Yes (50)
Concentration
  • 1 mCi/mL (3)
  • 1.0 - 10 mCi/mL (56)
  • 1.0 - 10 µCi/mL (3)
  • 1.12 mCi/mL (1)
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  • 2.93 MBq/mL (1)
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  • 33.7 µCi (1)
  • 345 µCi/mL (3)
  • 353 µCi/mL (1)
  • 41.4 µCi/mL (2)
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  • <1.0 mCi/mL (7)
  • <1.0 µCi/mL (3)
  • <100 µCi/mL (1)
Experimental Type
  • In vitro (4)
Format
  • Microplates (19)
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Host Cell
  • 1321N1 (11)
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  • L Cells (1)
  • MDA-MB-435S (1)
  • MDCK (2)
  • U373 (1)
  • UC11 (1)
Length
  • 51-100 (6)
Number of Wells
  • 96 (4)
Volume
  • 0-50 (43)
  • 51-100 (1)
  • 201-250 (55)

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