PerkinElmer

Quantitative Pathology Research

Tumor Microenvironment Opal 7 Color Image
Tumor Microenvironment Opal 7 Color Image

Stain

Simultaneously detect eight biomarkers plus DAPI within a single tissue section. Similar to standard immunohistochemistry, our advanced method is accessible to many laboratories where IHC method development is performed. It allows researchers to use the best primary antibodies, even those raised in the same species, together for multiplex detection. Our staining solutions provide researchers with tools to assess multiple cellular phenotypes at the same time while retaining context provided within tissue sections
Vectra® Polaris™ Automated Quantitative Pathology Imaging System
Vectra® Polaris™ Automated Quantitative Pathology Imaging System

Image

Our quantitative pathology imaging systems deliver high quality data where morphological context is preserved down to the sub-cellular level, removing autofluorescence and increasing signal-to-noise. These systems detect and measure multiple biomarkers, even if overlapping, within a single IHC or IF tissue section or TMA. Low signal levels that were previously undetected can now be captured, and overall quantification is vastly improved - particularly for solid, formalin-fixed, and paraffin-embedded tissues.
inform Image Analysis Software for Digital Pathology
inform Image Analysis Software for Digital Pathology

Analyze

Our software programs combine the latest technologies with algorithms and intuitive, easy-to-use interfaces, giving you the power to make new, exciting discoveries from your data. Our automated advanced image analysis software allows you to visualize, analyze, quantify and phenotype cells labeled with multiple biomarkers in situ in FFPE tissue sections.
Contract Research Services for Phenotyping In Situ
Contract Research Services for Phenotyping In Situ

Contract Research Services

Interested in testing the Phenoptics™ workflow? Our Research Services team can perform multiplexed IHC for up to seven colors (six markers plus DAPI) to help you get results.
Products & Services (18)
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Product Type
  • Instruments (3)
  • Reagents (11)
  • Software and Informatics (4)
Assay Target
  • and three open channels (1)
  • CD20 (3)
  • CD4 (4)
  • CD45RO (1)
  • CD68 (2)
  • CD8 (4)
  • FOXP3 (2)
  • panCK (2)
Target Species
  • Human (4)
Product Brand Name
  • Mantra (1)
  • Opal (9)
  • Vectra Polaris (1)
Detection Method
  • Brightfield (2)
  • Fluorescence (8)
  • MSI (6)
Fluorophore
  • Opal 520 (5)
  • Opal 540 (3)
  • Opal 570 (4)
  • Opal 570 and Opal 690 (1)
  • Opal 620 (3)
  • Opal 650 (3)
  • Opal 670 (1)
  • Opal 690 (3)
Automation Compatible
  • No (4)
  • Yes (3)
Technology
  • Multiplexed Biomarker Imaging (1)
Type
  • Opal 520 (1)
  • Opal 540 (1)
  • Opal 570 (1)
  • Opal 620 (1)
  • Opal 650 (1)
  • Opal 690 (1)

1-12 of 18 Products & Services

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  • Vectra image

    Vectra 3.0 Automated Quantitative Pathology Imaging System

    The Vectra® 3 automated quantitative pathology imaging system accurately detects and measures weakly expressed and overlapping biomarkers within a single H&E, IHC or IF intact FFPE tissue section or TMA to accelerate your cancer immunology research.
  • Vectra Polaris with monitor

    Vectra Polaris Automated Quantitative Pathology Imaging System

    The Vectra® Polaris Automated Quantitative Pathology Imaging System integrates both multispectral imaging and automated slide scanning to better visualize, analyze, quantify, and phenotype immune cells in situ in FFPE tissue sections and TMAs.
  • Mantra benchtop

    Mantra Quantitative Pathology Workstation

    Mantra quantitative pathology workstation with inForm® image analysis software enables easy visualization, quantification and phenotyping of multiple types of immune cells simultaneously in intact FFPE tissue sections for cancer immunology research.
  • 1X Plus Amplification Diluent

    1X Plus Amplification Diluent

    This patented, ready-to-use amplification diluent has been optimized specifically for Opal and TSA® Plus immunohistochemistry protocols. Used in conjunction with Opal or TSA Plus, the diluent facilitates signal amplification localized to the area of the target.
    List Price : 485.00 USD
  • Opal 650 Reagent Pack

    Opal Reagent Packs

    Opal is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.
    Price Range : 127.00 USD - 147.00 USD
  • Opal 4 Lymphocyte Kit, 50 slides

    Opal 4 Lymphocyte Kit

    The Opal 4 Tumor Lymphocyte Kit enables phenotyping of helper T cells, cytotoxic T cells and B cells within intact FFPE tissue sections.
    List Price : 1763.00 USD
  • PerkinElmer

    1X Plus Automation Amplification Diluent

    The 1x Plus Automation Amplification Diluent is formulated specifically for Opal multiplex IHC fluorophores used on the Leica BOND RX.
    List Price : 485.00 USD
  • Opal 7-Color Automation IHC Kit 50 slides - NEL801001KT

    Opal Automation IHC Kit 50 slides

    Opal is a practical workflow for the simultaneous detection of up to six tissue biomarkers plus nuclear counterstain within a single image. The method is similar to standard immunohistochemistry (IHC) and is accessible to many laboratories where standard IHC method development is performed.
    List Price : 1284.00 USD
  • Opal 7 Solid Tumor Immunology Kit, 25 slides

    Opal 7 Solid Tumor Immunology Kit

    The Opal 7 Solid Tumor Immunology Kit enables phenotyping of helper T cells, cytotoxic T cells, B cells, macrophages and cancer cells within intact FFPE tissue sections.
    List Price : 3741.00 USD
  • PerkinElmer

    Opal Automation IHC Kit 50 Slide

    Opal is a practical workflow for the simultaneous detection of up to six tissue biomarkers plus nuclear counterstain within a single image. The method is similar to standard immunohistochemistry (IHC) and is accessible to many laboratories where standard IHC method development is performed. The Opal 4-Color Automation Immunohistochemistry Kit is designed for use on the Leica Biosystems BOND RX, and is configured and validated for imaging on the Vectra® and Mantra systems. This kit contains reagents to stain 50-slides at the recommended dilution ratio.
    Price Range : 1006.00 USD - 1284.00 USD
  • Opal 7 Tumor Infiltrating Lymphocyte Kit

    Opal 7 Tumor Infiltrating Lymphocyte Kit

    The Opal Tumor Infiltrating Lymphocyte Kit enables phenotyping of T cells, B cells and cancer cells within intact FFPE tissue sections.
    List Price : 3741.00 USD
  • Opal Spectral DAPI

    Spectral DAPI

    This ready-to-use nucleic acid stain has been optimized specifically for Opal and TSA® Plus immunohistochemistry protocols.
    List Price : 61.00 USD
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