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Ginseng has been used as an herbal medicine in Asia for over two thousand years for its purported various health benefits, including antioxidant, anticarcinogenic, antiinflammatory, antihypertensive and anti-diabetic. The pharmacologically active compounds behind the claims of ginseng’s efficacy are ginsenosides; their underlying mechanism of action although not entirely elucidated appears to be similar to that of steroid hormones. There are a number of ginseng species, and each has its own set of ginsenosides.
This application note presents a fast and robust liquid chromatography method to simultaneously test nine widely used additives. Among the additives tested are: preservatives (benzoic acid, sorbic acid, dehydroacetic acid and methylparaben); artificial sweeteners (acesulfame potassium, saccharin and aspartame); flavoring agent (quinine); and a stimulant (caffeine).