PerkinElmer

Protein-Protein Interaction Research Reagents

OF

The interactions and binding of proteins are implicated in a large number of biological processes. The need for efficient, highly sensitive assays to study large protein interactions is increasingly important.

Notable, our Alpha technology is a highly flexible, homogenous, no-wash assay ideal for the measurement of protein interactions and complexes as large as 200 nm in size. A bead-based proximity assay, Alpha technology offers the possibility to assay many biological targets including enzymes, receptor-ligand interactions, low-affinity interactions, second messenger levels, DNA, RNA, proteins, peptides, sugars and small molecules.

The full measurement capabilities of our protein-protein interaction analysis technologies include:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

Products & Services (105)
Filters:
Assay Target
  • 4-1BB (1)
  • 4-1BBL (1)
  • CD28 (1)
  • CD86 (1)
  • EGF (2)
  • EGFR (3)
  • FCGR1 (1)
  • FCGR2A (2)
  • FCGR2B (1)
  • FCGR3A (2)
  • MMP-7 (1)
  • PD-1 (4)
  • PD-L1 (3)
  • PDL-1 (1)
  • TNFα (2)
  • TNRFR1 (1)
  • TNRFR3 (1)
Application
  • Antibody binding (1)
  • Enzymatic (5)
  • Isotyping (1)
  • Multiplexing (2)
  • Protein Analysis & Detection (49)
  • Protein Binding (3)
  • Protein-nucleic acid interactions (4)
  • Protein-protein interactions (91)
Therapeutic Area
  • Biologics/Bioprocess (6)
  • Cancer (7)
  • Immuno-oncology (3)
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Product Brand Name
  • Alpha (7)
  • AlphaLISA (44)
  • AlphaPlex (14)
  • AlphaScreen (12)
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  • LANCE SureLight (4)
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  • Alpha (62)
  • DELFIA TRF (6)
  • Time-Resolved Fluorescence (TRF) (23)
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Antibody Conjugates
  • Anti-6X His (1)
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  • Unconjugated (2)
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Assay Points (200-50,000)
  • 100 (5)
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Assay Target Class
  • Cytokine (2)
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  • Protein (12)
Automation Compatible
  • Yes (105)
Experimental Type
  • In vitro (73)
Format
  • Microplates (74)

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1-25 of 105 Products & Services

  • AlphaScreen Anti-Species

    AlphaScreen Mouse IgG Detection Kit

    AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-mouse IgG conjugated AlphaScreen Acceptor beads.
    Price Range : 214.00 USD - 16400.00 USD
  • LANCE® Eu-W1024 labeled anti-GST antibody

    Europium-labeled anti-GST antibody, for capturing GST-tagged proteins in LANCE® TR-FRET assays.
    Price Range : 230.00 USD - 11300.00 USD
  • PerkinElmer

    SureLight Allophycocyanin-anti-FLAG antibody, 1 mg, lyophilized

    APC-labeled anti-FLAG antibody, for capturing FLAG-tagged proteins and peptides in LANCE TR-FRET assays.
    List Price : 619.00 USD
  • AlphaLisa Analyte 2

    Biotinylated Human FCGR3A (176Val), lyophilized (AlphaLISA)

    Biotinylated human FCGR3A (176Val) receptor. For use in AlphaLISA® no-wash assays.
    List Price : 316.00 USD
  • AlphaLISA Acceptor Bead Antibody Coated

    Anti-V5 AlphaLISA Acceptor beads

    AlphaLISA® Acceptor beads conjugated to anti-V5 antibody. The mouse monoclonal antibody detects proteins tagged with the V5 14-amino-acid tag (the 9-amino-acid tag has also been successfully bound by the antibody). 
    Price Range : 700.00 USD - 28700.00 USD
  • AlphaLISA Sandwich Anti-AnalyteConjugatedAcceptorBead

    CD28/CD86 (human) AlphaLISA Binding Kit

    The AlphaLISA® human CD28/CD86 binding kit is designed for the detection of binding activity between human CD28 and CD86, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.

    Price Range : 2529.00 USD - 12600.00 USD
  • Protein G AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to Protein G. These beads can be used to capture antibodies that associate with Protein G.
    Price Range : 700.00 USD - 28700.00 USD
  • AlphaScreen General IgG (Protein A) Detection Kit

    AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Protein A conjugated AlphaScreen Acceptor beads.
    Price Range : 107.00 USD - 16400.00 USD
  • AlphaLISA Binding

    4-1BB/4-1BBL (human) AlphaLISA Binding Kit

    The AlphaLISA® 4-1BB/4-1BBL binding kit is designed for the detection of binding activity between human 4-1BB and 4-1BBL, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 2547.00 USD - 12700.00 USD
  • AlphaLISA Binding

    EGF/EGFR AlphaLISA Binding Kit

    The AlphaLISA® EGF/EGFR binding kit is designed for the detection of binding activity between human EGF and EGFR, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 828.00 USD - 11600.00 USD
  • AlphaLISA Acceptor Bead Antibody Coated

    Anti-HA AlphaLISA Acceptor Beads

    AlphaLISA Acceptor beads conjugated to anti-HA (hemagglutinin) antibody. These beads can be used to capture HA-tagged proteins and peptides.
    Price Range : 700.00 USD - 28800.00 USD
  • ULight anti-FITC

    ULight™ labeled anti-FITC antibody for LANCE® TR-FRET assays. The anti-FITC antibody is a purified mouse IgG2a monoclonal antibody.
    Price Range : 465.00 USD - 11800.00 USD
  • AlphaPlex Samarium Acceptor Beads

    Anti-Human IgG AlphaPlex 645 (Sm) Acceptor beads

    AlphaPlex™-645 (Samarium) Acceptor beads conjugated to anti-human IgG antibody, for use in Alpha no-wash multiplexing assays.
    Price Range : 700.00 USD - 28700.00 USD
  • AlphaLISA Binding

    FCGR3A/CD16a (176Val/V158) AlphaLISA Binding Kit

    This kit is designed for the detection of binding activity between human FCGR3A (176Val) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding.
    Price Range : 828.00 USD - 12600.00 USD
  • AlphaLISA Binding

    FcγR2A/CD32a (167H) AlphaLISA Binding Kit

    This kit is designed for the detection of binding between FCGR2A (CD32a) (167H) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
    Price Range : 2529.00 USD - 12600.00 USD
  • AlphaLISA Binding

    TNFα/TNFR2 (human) AlphaLISA Binding Kit

    The AlphaLISA® human TNFα/TNFR2 binding kit is designed for the detection of binding activity between human TNFα and TNFR2, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 2529.00 USD - 13000.00 USD
  • DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

    DELFIA Eu-N1 Streptavidin

    DELFIA® Europium-labeled streptavidin, for use in DELFIA time-resolved fluorescence (TRF) assays.
    List Price : 413.00 USD
  • LANCE Ultra Biomarker

    EGF-EGFR LANCE Ultra TR-FRET Binding Kit

    This kit is designed for the detection of binding activity between Human EGF and EGFR using a homogeneous LANCE Ultra TR-FRET assay. This assay can facilitate the design and development of therapeutics which competitively inhibit EGF/EGFR interaction.
    Price Range : 840.00 USD - 11200.00 USD
  • DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

    DELFIA® Eu-N1 Anti-HA

    Europium-labeled anti-HA antibody for binding HA-tagged proteins in DELFIA® time-resolved fluorescence (TRF) assays. The anti-HA antibody is a purified IgG2b subclass of mouse monoclonal antibody. It recognizes the epitope sequence (YPYDVPDYA) derived from the human influenza hemagglutinin (HA) protein.
    Price Range : 683.00 USD - 6600.00 USD
  • AlphaLISA Acceptor Bead Antibody Coated

    Anti-C-tag AlphaLISA Acceptor Beads

    AlphaLISA Acceptor beads conjugated to anti-C-tag antibody. These beads can be used to capture C-tag proteins, and can be used in conjunction with Alpha Donor beads to create AlphaLISA no-wash assays.
    Price Range : 701.00 USD - 28700.00 USD
  • AlphaPlex-545-antibody-bead2

    Anti-human IgG AlphaPlex 545 Acceptor Beads

    AlphaPlex™-545 (Terbium) Acceptor beads conjugated to anti-human IgG antibody, for use in Alpha no-wash multiplexing assays.
    Price Range : 700.00 USD - 28700.00 USD
  • Streptavidin-coated Alpha Donor Bead

    AlphaScreen Streptavidin Donor beads

    Alpha Donor beads coated with streptavidin, for biotinylated biomolecules for use in Alpha no-wash assays.
    Price Range : 429.00 USD - 12000.00 USD
  • AlphaScreen Anti-Species

    AlphaScreen C-MYC Detection Kit

    AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-c-myc-conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
    Price Range : 214.00 USD - 16400.00 USD
  • AlphaLISA Binding

    FcγR2A/CD32a (167R) AlphaLISA Binding Kit

    This kit is designed for the detection of binding between FCGR2A (CD32a) (167R) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
    Price Range : 2529.00 USD - 12600.00 USD
  • Protein A AlphaLISA Acceptor Beads

    AlphaLISA® Acceptor beads conjugated to Protein A. These beads can be used to capture antibodies that associate with Protein A.
    Price Range : 700.00 USD - 28700.00 USD
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