PerkinElmer

Protein-protein Interaction Research

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Protein-protein interaction research is uncovering new targets for drug discovery in cancer and a variety of other diseases. However, measurement, modulation, and detection of protein-protein interaction is challenging, and requires technology capable of measuring both high- and low-affinity interactions.

The full measurement capabilities of our protein-protein interaction analysis technologies include:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

Modulation of protein interactions can affect signal transduction, growth factor, gene expression, and other factors, making it a promising new avenue for protein-based treatment.

Development of protein-based therapeutics requires a thorough understanding of protein function and interactions. Our protein-protein interaction assays and instruments allow fast, multilabel detection of protein-protein interaction for drug discovery.

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  • Accessories (3)
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  • Reagents (107)
Assay Target
  • COX-2 (2)
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  • FCGR1 (1)
  • FCGR2A (2)
  • FCGR2B (1)
  • FCGR3A (2)
  • MMP-7 (1)
  • PD-1 (2)
  • PD-L1 (2)
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  • Human (9)
  • Mouse (1)
Application
  • Antibody binding (1)
  • Enzymatic (5)
  • Isotyping (1)
  • Multiplexing (2)
  • Protein Analysis & Detection (51)
  • Protein-nucleic acid interactions (4)
  • Protein-protein interactions (94)
Therapeutic Area
  • Biologics/Bioprocess (6)
  • Cancer (8)
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  • Alpha (6)
  • AlphaLISA (40)
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  • Image-based Cytometry (1)
  • Luminescence (4)
  • Time-Resolved Fluorescence (TRF) (30)
  • TR-FRET (19)
Antibody Conjugates
  • Anti-6X His (7)
  • Anti-bovine IgA (1)
  • Anti-c-Myc (4)
  • Anti-C-tag (3)
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  • Anti-DNP (2)
  • Anti-FITC (3)
  • Anti-FLAG (6)
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  • Anti-HRP (2)
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  • Anti-rabbit IgG (2)
  • Anti-rat IgG (2)
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Assay points(200-50,000)
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  • Fc-receptor (6)
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Automation Compatible
  • Yes (110)
Experimental Type
  • In vitro (76)
Format
  • Microplates (82)
Maximum Temperature (Celsius)
  • 40-50 (2)
  • 50-60 (2)

"Protein-protein Interaction Research" 1-50 of 115 Products and Services

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EnVision 2105 multimode plate reader

EnVision 2105 Multimode Plate Reader

The EnVision 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

The EnVision 2105 model delivers even higher sensitivity for time-resolved fluorescence (TRF) applications, and the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP). In addition, the Alpha 775 laser module is designed for plant assays.

EnSight Multimode Plate Reader

EnSight Multimode Plate Reader

The EnSight multimode plate reader combines labeled & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.
VictorX_ImageA_320px

VICTOR Multilabel Plate Reader

The VICTOR Multilabel plate reader has been replaced by the VICTOR Nivo multimode plate reader. Please contact your local representative for further information, or visit the VICTOR Nivo product page (Part Number - HH35000500).
EnSpire Alpha Plate Reader

EnSpire Alpha Plate Reader

The EnSpire Alpha Plate Reader provides proven Alpha technology to your lab at an affordable price and from the Alpha detection leader.

EnSpire Plate Reader is available outside the EU. Please contact your local representative for further details.

ViewLux uHTS Microplate Imager

ViewLux uHTS Microplate Imager

The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.

The ViewLux uHTS microplate imager is available outside the EU. Please contact your local representative to discuss alternative products.

LANCE Ultra ULight™-anti-GST

Goat polyclonal anti-GST tag antibody labeled with ULight™ dye.
Price Range : 471.00 USD - 11200.00 USD
Alphaplex_545_protein_coated

Streptavidin AlphaPlex™ 545 Acceptor Beads

Streptavidin-coated AlphaPlex™ 545 (Terbium) Acceptor beads, for use in Alpha no-wash multiplexing assays.
Price Range : 587.00 USD - 24100.00 USD
AlphaLISA immunoassay kits

FCGR2B/CD32b AlphaLISA Binding Kit

This kit is designed for the detection of binding between FCGR2B (CD32b) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
Price Range : 2123.00 USD - 10600.00 USD

ULight anti-c-myc antibody

ULight labeled anti-c-myc antibody for LANCE® TR-FRET assays.
Price Range : 428.00 USD - 10800.00 USD

AlphaScreen DIG (Digoxin/Digoxigenin) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-Dig (digoxin) conjugated AlphaScreen Acceptor beads. 
Price Range : 180.00 USD - 13800.00 USD

AlphaScreen Mouse IgG Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-mouse IgG conjugated AlphaScreen Acceptor beads.
Price Range : 180.00 USD - 13800.00 USD
DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

DELFIA Sm-N1 Streptavidin

Samarium-labeled streptavidin for binding biotinylated biomolecules in DELFIA® time-resolved fluorescence (TRF) assays.
Price Range : 307.00 USD - 2092.00 USD

Anti-V5 AlphaLISA Acceptor beads

AlphaLISA® Acceptor beads conjugated to anti-V5 antibody. The mouse monoclonal antibody detects proteins tagged with the V5 14-amino-acid tag (the 9-amino-acid tag has also been successfully bound by the antibody). 
Price Range : 588.00 USD - 24100.00 USD
PerkinElmer

LANCE Eu-W1024 anti-FLAG

Eu-W1024 labeled anti-FLAG antibodies for LANCE® TR-FRET assays. The anti-FLAG antibody is a purified mouse IgG2a monoclonal antibody (clone 29E4.G7.H11). The antibody is know to recognize C-terminal and N-terminal FLAG-tagged proteins.
Price Range : 402.00 USD - 9000.00 USD
LANCE Detection Kit

EGF-EGFR LANCE Ultra TR-FRET Binding Kit

This kit is designed for the detection of binding activity between Human EGF and EGFR using a homogeneous LANCE Ultra TR-FRET assay. This assay can facilitate the design and development of therapeutics which competitively inhibit EGF/EGFR interaction.
Price Range : 773.00 USD - 10300.00 USD

Anti-bovine IgA AlphaLISA Acceptor Beads

AlphaLISA Acceptor beads conjugated to anti-bovine IgA antibody. These beads can be used to capture bovine IgA antibodies.
Price Range : 797.00 USD - 26900.00 USD

AlphaScreen Histidine (Nickel Chelate) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and nickel chelate (Ni-NTA) AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
Price Range : 180.00 USD - 13800.00 USD

ULight anti-FITC

ULight™ labeled anti-FITC antibody for LANCE® TR-FRET assays. The anti-FITC antibody is a purified mouse IgG2a monoclonal antibody.
Price Range : 428.00 USD - 10800.00 USD
PerkinElmer

LANCE Eu-W1024 Streptavidin

Europium-labeled streptavidin, for capturing biotinylated biomolecules in LANCE TR-FRET assays.
Price Range : 1043.00 USD - 9100.00 USD
AlphaLISA binding assay principle

PD-1/PD-L1 (human) AlphaLISA Binding Kit

The AlphaLISA® PD-1/PD-L1 Binding Kit is designed for the detection of binding activity between Human PD-1 and PD-L1, using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of therapeutics which competitively inhibit PD-1/PD-L1 interaction.
Price Range : 695.00 USD - 9700.00 USD

AlphaScreen FITC (Fluorescein) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-FITC conjugated AlphaScreen Acceptor beads. 
Price Range : 192.00 USD - 13800.00 USD

AlphaLISA anti-mouse IgG Acceptor beads

AlphaLISA Acceptor beads conjugated to anti-mouse IgG antibody. This antibody is not Fc-specific; for Fc-specific beads, please see product AL105.
Price Range : 565.00 USD - 23200.00 USD

AlphaScreen HA (Hemagglutinin) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-HA (hemagglutinin) conjugated AlphaScreen Acceptor beads. 
Price Range : 183.00 USD - 13800.00 USD
Alphaplex-545-terbium-glutathione

Glutathione AlphaPlex™ 545 Acceptor Beads

AlphaPlex™-545 (Terbium) Acceptor beads conjugated to glutathione, for use in Alpha no-wash multiplexing assays.
Price Range : 587.00 USD - 24100.00 USD
AlphaPlex-545-antibody-bead2

Anti-6X His AlphaPlex-545 (Tb) Acceptor beads

AlphaPlex-545 Acceptor beads conjugated to anti-6XHis antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 587.00 USD - 24100.00 USD

Anti-C-tag AlphaLISA Acceptor Beads

AlphaLISA Acceptor beads conjugated to anti-C-tag antibody. These beads can be used to capture C-tag proteins, and can be used in conjunction with Alpha Donor beads to create AlphaLISA no-wash assays.
Price Range : 588.00 USD - 24100.00 USD
PerkinElmer

SureLight Allophycocyanin-anti-6His antibody, 1 mg, lyophilized

APC-labeled anti-His antibody, for capturing His-tagged proteins and peptides in LANCE TR-FRET assays.
List Price : 570.00 USD
PerkinElmer

SureLight Allophycocyanin-streptavidin (APC-SA), protein binding assay, Iyophilized

APC-labeled streptavidin, for use in LANCE® TR-FRET protein binding assays.
Price Range : 397.00 USD - 11200.00 USD

Anti-rat IgG (Fc specific) AlphaLISA® Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-rat IgG antibody. These beads can be used to capture rat IgG antibodies. The antibody is Fc-specific, and is a goat polyclonal F(ab')2 fragment.
Price Range : 588.00 USD - 24100.00 USD

Anti-FITC AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to mouse monoclonal anti-FITC antibody. These beads can be used to capture FITC-tagged and fluorescein-labeled biomolecules for AlphaLISA no-wash assays.
Price Range : 588.00 USD - 24100.00 USD
PerkinElmer

LANCE Eu-W1024 anti-FITC

Eu-W1024 labeled anti-FITC antibodies for LANCE® TR-FRET assays. The anti-FITC antibody is a purified mouse IgG2a monoclonal antibody.
Price Range : 318.00 USD - 8900.00 USD

Anti-Maltose-Binding Protein (MBP) AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to anti-MBP (maltose-binding protein) antibody. The antibody is a rat monoclonal antibody, clone MBP 7G4. These beads can be used to capture MBP-tagged proteins for AlphaLISA no-wash assays.
Price Range : 588.00 USD - 24100.00 USD
AlphaPlex-545-antibody-bead2

Anti-rabbit IgG AlphaPlex-545 (Tb) Acceptor Beads

AlphaPlex™-545 (Terbium) Acceptor beads conjugated to anti-rabbit IgG antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 587.00 USD - 24100.00 USD

Strep-Tactin® AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to Strep-Tactin®. These beads can be used to capture Strep-tag® II-tagged proteins for AlphaLISA no-wash assays.
Price Range : 571.00 USD - 23500.00 USD

Nickel Chelate AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to nickel chelate. These beads can be used to capture His-tagged proteins and peptides.
Price Range : 588.00 USD - 24100.00 USD
Alpha donor antibody coated

Anti-HRP Alpha Donor Beads

Alpha Donor beads conjugated to anti-HRP antibody. These beads can be used to capture HRP-fusion proteins for Alpha no-wash detection, binding, and other assays.
Price Range : 467.00 USD - 8400.00 USD

Anti-HA AlphaLISA Acceptor Beads

AlphaLISA Acceptor beads conjugated to anti-HA (hemagglutinin) antibody. These beads can be used to capture HA-tagged proteins and peptides.
Price Range : 588.00 USD - 24100.00 USD

MMP-7 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human MMP7 enables the detection and quantitation of human pro- and active MMP-7 (hMMP-7) in serum, buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 446.00 USD - 9700.00 USD

ULight anti-FLAG

ULight™ labeled anti-FLAG antibodies for LANCE® TR-FRET assays. The anti-FLAG antibody is a purified mouse IgG2a monoclonal antibody (clone 29E4.G7.H11). The antibody is know to recognize C-terminal and N-terminal FLAG-tagged proteins.
Price Range : 435.00 USD - 10600.00 USD

AlphaScreen Rabbit IgG Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-rabbit IgG conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
Price Range : 180.00 USD - 13800.00 USD

Anti-HRP AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-HRP antibody. These beads can be used to capture HRP-fusion proteins for AlphaLISA no-wash assays.
Price Range : 571.00 USD - 23400.00 USD

Anti-GST AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-GST antibody. These beads can be used to capture GST-tagged proteins and peptides in AlphaLISA no-wash assays.
Price Range : 588.00 USD - 24100.00 USD
PerkinElmer

Protein A AlphaPlex™ 545 Acceptor Beads

AlphaPlex™-545 (Terbium) Acceptor beads conjugated to Protein A, for use in Alpha no-wash multiplexing assays.
Price Range : 587.00 USD - 24100.00 USD

AlphaScreen General IgG (Protein A) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Protein A conjugated AlphaScreen Acceptor beads.
Price Range : 90.00 USD - 13800.00 USD

Anti-c-myc AlphaLISA® Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-c-myc antibody. These beads can be used to capture c-myc-tagged proteins and peptides in AlphaLISA no-wash assays.
Price Range : 588.00 USD - 24100.00 USD
Alpha_Donor_bead_1

AlphaScreen Streptavidin Donor beads

Alpha Donor beads conjugated to streptavidin.
Price Range : 360.00 USD - 10100.00 USD
AlphaPlex Samarium Acceptor Beads

Anti-6X His AlphaPlex 645 (Sm) Acceptor beads

AlphaPlex™-645 (Samarium) Acceptor beads conjugated to anti-6XHis antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 587.00 USD - 24100.00 USD
PerkinElmer

LANCE Eu-W1024 Anti-HA

Europium-labeled anti-HA antibody, for capturing HA-tagged proteins and peptides in LANCE® TR-FRET assays.
Price Range : 1043.00 USD - 13900.00 USD

AlphaScreen C-MYC Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-c-myc-conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
Price Range : 180.00 USD - 13800.00 USD
AlphaPlex-545-antibody-bead2

Anti-FLAG AlphaPlex-545 (Tb) Acceptor beads

AlphaPlex-545 (Terbium) Acceptor beads conjugated to anti-FLAG antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 587.00 USD - 24100.00 USD

"Protein-protein Interaction Research" 1-50 of 115 Products and Services

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