PerkinElmer

Metabolic Disease

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Metabolic diseases like diabetes are increasingly widespread, and research for this class of diseases relies on discovering and quantifying biomarkers to elucidate underlying mechanisms and uncover novel drug targets. Our portfolio of metabolic assays are well suited for metabolic disease research in vitro, in vivo, and in situ, and offer novel tools for your research workflow from start to finish.

Metabolic diseases are systemic and manifest with a variety of biological changes, from autophagy dysfunction to altered blood coagulation. For easy detection of a wide range of metabolic biomarkers, we offer fast and pre-validated metabolic assay reagents, kits, and imaging systems. For targeted binding studies, we also provide target-specific radiolabeled reagents.

Our products for metabolic disease research include:

  • LANCE® TR-FRET technology
  • AlphaLISA® immunoassay kits
  • Alpha reagents for AlphaLISA
  • DELFIA® TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Target-specific radiolabeled ligands, carbohydrates, lipids, and steroids

The range of tools offered allows for the detection and quantitation of many key biomolecules in metabolic disease research. Gain precise insight on disease biomarkers like c-reactive protein, fibrinogen, IGF, FGF, insulin and glucagon, leptin and ghrelin, adiponectin, and factor VIII.

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Product Type
  • Instruments (1)
  • Reagents (140)
  • Software and Informatics (4)
Assay Target
  • Adiponectin (3)
  • Albumin (5)
  • ApoA1 (4)
  • ApoB (2)
  • ApoC3 (2)
  • ApoE (2)
  • AST (1)
  • BMP-9 (1)
  • C-peptide (2)
  • CCL2 (1)
  • Corticosterone (2)
  • Cortisol (3)
  • Factor VIII (1)
  • FSH (3)
  • Ghrelin (4)
  • GLP-1 (2)
  • Glucagon (3)
  • Growth Hormone (1)
  • hCG (3)
  • HO-1 (1)
  • HO-2 (1)
  • IGF1 (5)
  • IGF2 (1)
  • Insulin (4)
  • KIM-1 (1)
  • LDH (1)
  • Leptin (5)
  • MANF (2)
  • MBNL1 (1)
  • NNMT (1)
  • Osteoprotegerin (1)
  • PCSK9 (1)
  • PIGF (1)
  • PON1 (1)
  • PON2 (1)
  • Progesterone (1)
  • PSMA (2)
  • SHP2 (1)
  • Somatostatin (1)
  • Testosterone (1)
  • TSH (4)
  • Utrophin (1)
Target Species
  • Human (76)
  • Mouse (5)
  • Rat (4)
Application
  • Protein Analysis & Detection (82)
Therapeutic Area
  • Angiogenesis (1)
  • Biologics/Bioprocess (4)
  • Cancer (4)
  • Central Nervous System (1)
  • Inflammation (4)
  • Metabolic (62)
Product Brand Name
  • AlphaLISA (53)
  • AlphaPlex (2)
  • LANCE Ultra (28)
  • Membrane Target Systems (1)
  • NEN Radiochemicals (54)
  • Quantum (1)
Detection Method
  • Alpha (55)
  • Radiometric (55)
  • Time-Resolved Fluorescence (TRF) (25)
  • TR-FRET (25)
Receptor Type
  • Ghrelin (1)
Assay Validated
  • Binding (1)
Radioisotope
  • C-14 (27)
  • H-3 (28)
Radionuclide
  • 14C (27)
  • 3H (28)
Label Position
  • Generally Labeled (2)
  • Nominally Labeled (17)
  • Specifically Labeled (25)
  • Uniformly Labeled (11)
Buffer
  • Aqueous (10)
  • Aqueous PT6-271 Stabilizer (2)
  • Ethanol : water (10)
Assay points(200-50,000)
  • 100 (28)
  • 10000 (16)
  • 500 (55)
  • 5000 (40)
Assay Target Class
  • Cytokine (1)
  • GPCR (1)
  • Hormone (37)
  • Peptide (5)
  • Protein (42)
Automation Compatible
  • Yes (84)
Concentration
  • 0.02 mCi/mL (1)
  • 0.05 mCi/mL (1)
  • 0.1 mCi/mL (11)
  • 0.2 mCi/mL (4)
  • 1 mCi/mL (17)
Experimental Type
  • In vitro (70)
Format
  • Microplates (67)
Host Cell
  • CHO-K1 (1)
Imaging Modality
  • microCT Imaging (1)
Length
  • 901-1000 (1)
Pipetting Arms
Volume
  • 0-50 (15)
  • 201-250 (4)

"Metabolic Disease" 1-50 of 145 Products & Services

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Quantum GX2 microCT imaging system

Quantum GX2 microCT Imaging System

Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.
AlphaLISA immunoassay kits

Cortisol (human) AlphaLISA Detection Kit

AlphaLISA no-wash immunoassay kit for detection of human cortisol in buffer or serum.
Price Range : 725.00 USD - 10500.00 USD

Apo-CIII (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Apo-CIII Detection Kit is designed for detection and quantitation of ApoC3 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 806.00 USD - 10700.00 USD
Adenosine 5 Triphosphate 250 µCi

Myo-inositol, [3H], 1 mCi

Myo-inositol, [3H]- will have fresh lot dates on the second Monday in March and September.
List Price : 3261.00 USD

ApoA1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for ApoA1 is designed for the quantitative determination of ApoA1 in human serum, human plasma and cell supernantants using a homogeneous AlphaLISA assay (no wash steps). Neglible cross reactivity was observed with ApoCIII, ApoE, or ApoB.
Price Range : 644.00 USD - 19300.00 USD
Adenosine 5 Triphosphate 250 µCi

Glucose, D-[6-3H(N)]

D-glucose, labeled with tritium at C6. This product is supplied in 90% ethanol. D-glucose can be used for metabolic studies and glucose uptake.
Price Range : 668.00 USD - 2442.00 USD

CCL2 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human CCL2/MCP-1 Detection Kit is designed for detection and quantitation of human CCL2/MCP-1 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 830.00 USD - 11000.00 USD
Diclofenac sodium- Phenylacetic acid C14

Glucose, D- [U-14C]-

250 µCi quantities of D-[14C(U)]-Glucose are available for your research.
List Price : 1685.00 USD
LANCE Detection Kit

ApoE (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human ApoE Detection Kit is designed for detection and quantitation of human Apolipoprotein E (ApoE) in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 806.00 USD - 10700.00 USD
LANCE Detection Kit

Leptin (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Leptin Detection Kit is designed for detection and quantitation of human leptin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 830.00 USD - 11000.00 USD
alphaimmunoassay1

Growth Hormone (human) AlphaLISA Detection Kit

The AlphaLISA® Human Growth Hormone Detection Kit is designed for detection and quantitation of human growth hormone in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1693.00 USD - 10500.00 USD
AlphaLISA immunoassay kits

PSMA (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human PSMA enables the quantitative determination of human prostate specific membrane antigen (PSMA) in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 625.00 USD - 15000.00 USD
Adenosine 5 Triphosphate 250 µCi

Inulin, Methoxy-, [Methoxy-3H]

Methoxy-inulin, labeled on methoxy groups with tritium. 3H-methoxyinulin is commonly used to measure glomerular fitration rates (GFR) or as an extracellular space marker.
Price Range : 735.00 USD - 2318.00 USD
Diclofenac sodium- Phenylacetic acid C14

Glycerol, [14C(U)]

Glycerol, uniformly labeled with C-14. 14C-glycerol is commonly used to label carbohydrates.
Price Range : 826.00 USD - 2812.00 USD
AlphaLISA immunoassay kits

KIM-1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human Kidney Injury Molecule 1 (KIM-1) enables the quantitative determination of human KIM-1 in buffered solution, urine, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 759.00 USD - 14600.00 USD

Factor VIII (human) AlphaLISA Detection Kit

The AlphaLISA® Human Factor VIII Detection Kit is designed for detection and quantitation of Human Factor VIII in human serum, plasma, and cell culture supernatants using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 672.00 USD - 10500.00 USD

Utrophin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human utrophin enables the quantitative determination of utrophin in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 301.00 USD - 18800.00 USD
Adenosine 5 Triphosphate 250 µCi

Glucosamine Hydrochloride, D-[6-3H(N)]-, Aqueous solution, Specific Activity: 20-45Ci (740GBq-1.66TBq)/mmol, 1mCi (37MBq)

1 mCi quantities of tritiated D-glucosamine hydrochloride are available for your research.
List Price : 1235.00 USD
Diclofenac sodium- Phenylacetic acid C14

Deoxy-D-glucose, 2-[1-14C]-, in Ethanol/Water

2-Deoxy-D-glucose, labeled with carbon-14 at C1. This product is supplied in 90% ethanol. Deoxy-D-glucose (DOG) is a glucose analog that is readily transported into most cells, is phosphorylated and trapped by the cells (unidirectional transport), and cannot be further metabolized. It is the most-common chemical used in glucose uptake assays.
Price Range : 1181.00 USD - 5400.00 USD

Leptin (mouse) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Mouse Leptin Detection Kit is designed for detection and quantitation of mouse leptin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 830.00 USD - 11100.00 USD
Adenosine 5 Triphosphate 250 µCi

Galactose, D-[1-14C]

50 µCi quantities of D-[1-14C]-Galactose are available for your research.
List Price : 1254.00 USD
AlphaLISA immunoassay kits

hCG (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human chorionic gonadotropin (hCG) enables the quantitative determination of hCG in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 541.00 USD - 16200.00 USD

PIGF (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human placental growth factor (PIGF) enables the quantitative determination of human PIGF (PGF) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 451.00 USD - 9900.00 USD

Albumin (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Albumin Detection Kit is designed for detection and quantitation of human albumin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 829.00 USD - 11100.00 USD
AlphaLISA assay principle

BMP-9 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human BMP-9 enables the quantitative determination of human Bone Morphogenetic Protein 9 (BMP-9) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 625.00 USD - 18800.00 USD
AlphaLISA immunoassay kits

NNMT (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human Nicotinamide N-Methyltransferase (NNMT) enables the quantitative determination of human NNMT in buffered solution, cell culture media, and serum using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 759.00 USD - 14600.00 USD
Adenosine 5 Triphosphate 250 µCi

Inositol, Myo,-[2-3H(N)]-, Ethanol/Water

Myo-inositol, labeled with tritium. This product is supplied in 90% ethanol. Tritiated myoinositol is commonly used to label lipids.
Price Range : 1964.00 USD - 4929.00 USD

Myo-inositol,-[2-3H]

1 mCi quantities of Myo-[2-3H]-Inositol are available for your research.
List Price : 3123.00 USD
Diclofenac sodium- Phenylacetic acid C14

Glucose 1-Phosphate, α-D-[14C(U)]-, Dipotassium Salt, 50µCi (1.85MBq)

50 µCi quantities of α-D-[14C(U)]-Glucose 1-Phosphate, Dipotassium Salt are available for your research.
List Price : 1551.00 USD
AlphaPlex Samarium immunoassay kits

AlphaPlex-645 (Sm) Human Insulin Detection Kit

The AlphaPlex™ 645 (Samarium) Human Insulin Detection Kit is designed for the quantitative determination of human insulin together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous (no wash steps, no separation steps) assay.
Price Range : 480.00 USD - 10500.00 USD
Diclofenac sodium- Phenylacetic acid C14

Glucose, D-[14C(U)]-, Specific Activity: 1-5mCi (37.0-185MBq)/mmol, 1mCi (37MBq)

1 mCi quantities of D-[14C(U)]-Glucose are available for your research.
List Price : 2595.00 USD
Diclofenac sodium- Phenylacetic acid C14

Inulin, Carboxyl-, [Carboxyl-14C]

Inulin-carboxyl, labeled on carboxyl groups with C-14. Inulin-carboxyl-14C is commonly used in renal cearance studies.
Price Range : 599.00 USD - 2970.00 USD
AlphaLISA immunoassay kits

Insulin-like Growth Factor 2 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Insulin-like Growth Factor 2 (IGF2) Detection Kit is designed for detection and quantitation of human IGF2 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1585.00 USD - 10500.00 USD
AlphaLISA immunoassay kits

Glucagon (human) AlphaLISA Detection Kit

The AlphaLISA® Glucagon Detection Kit is designed for detection and quantitation of glucagon in cell culture media, sera and plasma, in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 725.00 USD - 10100.00 USD
Alpha Bungarotoxin

Methyl α-D-glucopyranoside, [Glucose-14C(U)]-, 250µCi (9.25MBq)

250 µCi quantities of [Glucose-14C(U)]-Methyl α-D-glucopyranoside are available for your research.
List Price : 4020.00 USD
AlphaLISA immunoassay kits

Insulin-like Growth Factor 1 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Insulin-like Growth Factor 1 (IGF1) Detection Kit is designed for detection and quantitation of human IGF1 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1585.00 USD - 10500.00 USD

Adiponectin (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Adiponectin Detection Kit is designed for detection and quantitation of human adiponectin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 830.00 USD - 11100.00 USD
AlphaLISA immunoassay kits

PON-1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human paraoxonase/arylesterase 1 (PON-1) enables the quantitative determination of human PON-1 in buffered solution, serum, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 759.00 USD - 14600.00 USD
AlphaLISA immunoassay kits

FSH (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human FSH enables the quantitative determination of human follicle stimulating hormone in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 541.00 USD - 16200.00 USD
LANCE Detection Kit

PCSK9 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human PCSK9 Detection Kit is designed for detection and quantitation of human Proprotein Convertase Subtilisin/Kexin Type 9 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 829.00 USD - 11100.00 USD
AlphaLISA immunoassay kits

PON-2 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human PON-2 enables the quantitative determination of human Paraoxonase 2 (PON-2) in buffered solution, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 759.00 USD - 14600.00 USD
Adenosine 5 Triphosphate 250 µCi

Deoxy-D-glucose, 2-[1,2-3H(N)]

2-Deoxy-D-glucose, labeled with tritium at C1/C2. Deoxy-D-glucose (DOG) is a glucose analog that is readily transported into most cells, is phosphorylated and trapped by the cells (unidirectional transport), and cannot be further metabolized. It is the most-common chemical used in glucose uptake assays.
Price Range : 792.00 USD - 3327.00 USD
Diclofenac sodium- Phenylacetic acid C14

Methyl-D-glucose, 3-O-[Methyl-14C]

3-O-methyl-D-glucose, labeled on the methyl group with C-14. 3-O-methyl-D-glucose (OMG) is a glucose analog that is readily transported into most cells, but does not become phosphorylated and therefore will equilibrate across the cell membrane. Equilibrium is usually reached rapidly, so glucose uptake assays may only be linear for a short period of time; you may need to take your measurements fairly quickly. This analog cannot be further metabolized by cells.
Price Range : 1005.00 USD - 3136.00 USD
Diclofenac sodium- Phenylacetic acid C14

Methyl α-D-glucopyranoside, [Glucose-14C(U)]-, 50µCi (1.85MBq)

50 µCi quantities of [Glucose-14C(U)]-Methyl α-D-glucopyranoside are available for your research.
List Price : 1195.00 USD
AlphaLISA immunoassay kits

Somatostatin (human) AlphaLISA Detection Kit

The AlphaLISA® Somatostatin Detection Kit is designed for detection and quantitation of somatostatin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 725.00 USD - 10500.00 USD
Adenosine 5 Triphosphate 250 µCi

Glucose, D-[5-3H(N)]-, 1mCi (37MBq)

1 mCi quantities of D-[5-3H(N)]-Glucose are available for your research. 
List Price : 1635.00 USD
AlphaLISA immunoassay kits

Insulin (human) AlphaLISA Detection Kit

The AlphaLISA® Human Insulin Detection Kit is designed for detection and quantitation of human insulin in cell culture supernatants, serum, and plasma using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 725.00 USD - 10200.00 USD
Protein

Chorionic gonadotropin (human), lyophilized (LANCE)

Human chorionic gonadotropin (hCG) standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra hCG Detection Kit, but can also be ordered separately.
List Price : 308.00 USD
AlphaLISA immunoassay kits

MBNL1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human muscleblind-like protein 1 (MBNL1) enables the quantitative determination of human MBNL1 in buffered solution and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 1821.00 USD - 14600.00 USD
LANCE Detection Kit

GLP-1 (7-36) (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human GLP-1 (7-36) Detection Kit is designed for detection and quantitation of human GLP-1 (7-36) in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 829.00 USD - 11100.00 USD

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