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Iodinated Compounds

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Radiometric detection is considered the gold standard for many applications, from drug discovery and development to plant sciences. 125I labeled compounds are useful in both basic research and drug discovery where they are used as tracers in radioimmunoassays (RIA) and ligands in binding studies. 125I is particularly versatile as it emits both gamma and Auger electrons. This means that can be it counted either directly, without requiring scintillation, or by using a liquid scintillation counter. We offer a wide range of 125I labeled compounds as well as customized services to label your unique compound.

We also provide customized services to 131I labeled your compound of interest.

For Research and investigative use only.

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"Iodinated Compounds" 1-50 of 78 Products and Services

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Ornithine Vasotocin Analog, [125I]-OVTA)

Ornithine Vasotocin Analog (OVTA), labeled with 125I. OVTA binds oxytocin receptors, a hormone receptor involved in pregnancy, milk production, stress, social memory, and bonding.
Price Range : 1098.00 USD - 2226.00 USD

Apamin [125I]His18-NH2

Apamin, labeled with 125I on histidine residue 18. Apamin is a neurotoxin that acts as an antagonist at calcium-activated potassium channels (SK channels).
Price Range : 910.00 USD - 1514.00 USD

MCP-1,[125I]- labeled, Bolton-Hunter Labeled

Monocyte chemoattractant protein 1 (MCP-1; CCL2), labeled with 125I. MCP-1 is a cytokine released by tumor cells that binds chemokine receptor 2 (CCR2).
Price Range : 733.00 USD - 1728.00 USD

Endothelin-1 (human, porcine), [125I]Tyr13

Endothelin-1 (ET-1), labeled with 125I on the tyrosine 13 residue. Endoethlin-1 is a vasoconstrictor that acts as an endogenous agonist at endothelin receptors. Endothelin receptors are a class of GPCRs that are potential drug targets for hypertension and cancer.
Price Range : 912.00 USD - 2510.00 USD

RTI-55, [125I]

RTI-55, labeled with 125I. RTI-55 is a nonselective dopamine reuptake inhibitor that is used to assess neuron degradation in Parkinson's disease and other neurodegenerative diseases.
Price Range : 904.00 USD - 1801.00 USD

Insulin-like Growth Factor-I (human, recombinant), 125I

Insulin-like growth factor 1 (IGF-1), labeled with 125I. IGF-1 acts as an agonist at the IGF-1 receptor, a receptor tyrosine kinase, that plays a role in growth, cancer, and aging. IGF-1 also binds the insulin receptor (IR), another receptor tyrosine kinase involved in glucose homeostasis, diabetes, and cancer.
Price Range : 675.00 USD - 1656.00 USD

Neurokinin B, [125I]His, MePhe7

Neurokinin B (NKB), labeled with 125I on the histidine residue. Neurokinin B is involved in ovarian cycle regulation, and binds neurokinin 3 receptor (NK3R; tachykinin receptor 3), a GPCR involved in vascular remodeling, angiogenesis, and cancer.
Price Range : 980.00 USD - 2283.00 USD

Somatostatin, [125I]Tyr11

Somatostatin, labeled with 125I. Somatostatin binds somatostatin receptors, and inhibits the secretion of insulin and glucagon.
Price Range : 904.00 USD - 2107.00 USD

CGRP (human), [125I]

Calcitonin gene-related peptide (CGRP), labeled with 125I. CGRP binds calcitonin receptors.
Price Range : 797.00 USD - 1932.00 USD

[125I]- Epidermal Growth Factor (human, rat)

NEX428 Epidermal Growth Factor is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
Price Range : 725.00 USD - 1599.00 USD

IL-6 (human, recombinant), [125I]

Interleukin 6 (IL-6), labeled with 125I. IL-6 is a cytokine that regulates cell growth, cell differentiation, and immune response, and binds to the interleukin 6 receptor (IL6R; CD126).
Price Range : 1290.00 USD - 4316.00 USD

Ω-Conotoxin GVIA, [125I] Tyr22

Ω-Conotoxin GVIA (ω-Conotoxin GVIA), labeled with 125I on tyrosine residue 22. Omega conotoxin CVIA is a calcium channel blocker.
Price Range : 625.00 USD - 1999.00 USD

Human Growth Hormone, [125I]

Human growth hormone (HGH), labeled with 125I. Human growth hormone stimulates growth, cell reproduction and regeneration in animals. HGH functions to regulate body composition, fluid homeostasis, glucose and lipid metabolism, skeletal muscle and bone growth.
Price Range : 880.00 USD - 2359.00 USD

MIP-1α (human, recombinant), [125I]

Human recombinant macrophage inflammatory protein 1-alpha (MIP-1α; CCL3), labeled with 125I. MIP-1α is a cytokine involved in acute inflammation, and binds C-C chemokine receptors CCR1, CCR4, and CCR5.
Price Range : 735.00 USD - 3014.00 USD

Iodoaminopotentidine, [125I]

NEX431 [125I]-Aminopotentidine has been shown to work in receptor binding and autoradiography and is an antagonist for histamine (H2) receptors.
Price Range : 855.00 USD - 1931.00 USD

Triiodothyronine, ([125I]-T3), Specific Activity: 3300 µCi/µg

Triiodothyronine (T3) labeled with 125I. Triiodothyronine is a thyroid hormone that affects growth and development, body temperature, and heart rate. T3 detection by radioimmunoassay is a common test of thyroid gland function. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
Price Range : 744.00 USD - 2513.00 USD

Angiotensin I (human), [125I]Tyr4

Angiotensin I, labeled with 125I on the tyrosine (Tyr4) residue. Angiotensin I is the precursor to Angiotensin II, which a peptide hormone that causes vasoconstriction and increased blood pressure, and is a potential drug target for blood pressure regulation.
Price Range : 857.00 USD - 2054.00 USD

Iodo-(-)-Cyanopindolol, [125I]

Iodo-(-)-cyanopindolol, labeled with 125I. Cyanopindolol acts as an antagonist at β1 adrenergic receptors and serotonin 5-HT1A receptors.
Price Range : 1085.00 USD - 1770.00 USD

Triiodothyronine, ([125I]-T3), Specific Activity: 135-165 µCi/µg

Triiodothyronine (T3) labeled with 125I. Triiodothyronine is a thyroid hormone that affects growth and development, body temperature, and heart rate. T3 detection by radioimmunoassay is a common test of thyroid gland function. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
Price Range : 675.00 USD - 1701.00 USD

α-Bungarotoxin, [125I]-Tyr54

α-bungarotoxin, labeled with 125I on tyrosine residue 54. α-bungarotoxin is a snake venom neurotoxin that acts as an antagonist at nicotinic acetylcholine receptors (nAChRs). This product as offered at two specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available). This indicates that virtually every molecule of ligand provided in the stock vial is radiolabeled.
Price Range : 566.00 USD - 2527.00 USD

IP-10 (human, recombinant), [125I]-, Bolton-Hunter Labeled

Interferon gamma-induced protein 10 (IP-10; CXCL10), labeled with 125I. IP-10 binds the chemokine CXCR3 receptor, and is secreted in response to IFN-γ.
Price Range : 744.00 USD - 1804.00 USD

Triiodothyronine, ([125I]-T3), Specific Activity: 1080-1320 µCi/µg

Triiodothyronine (T3) labeled with 125I. Triiodothyronine is a thyroid hormone that affects growth and development, body temperature, and heart rate. T3 detection by radioimmunoassay is a common test of thyroid gland function. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
Price Range : 787.00 USD - 2272.00 USD

GLP-1 (7-36), [125I]

Glucagon-like peptide-1 (GLP-1), labeled with 125I. GLP-1 is a peptide hormone involved in secretion of insulin, and binds and activates GLP-1 receptors, a member of the glucagon receptor family of GPCRs.
Price Range : 1219.00 USD - 2224.00 USD

Pancreatic Polypeptide (human), [125I]

Human pancreatic polypeptide (PP), labeled with 125I. Pancreatic polypeptide acts as an agonist at Pancreatic polypeptide receptors (Neuropeptide Y receptors), a class of GPCRs involved in appetite, circadian rhythm, and anxiety.
Price Range : 1011.00 USD - 2288.00 USD

Sauvagine, [125I]-Tyr0]

Sauvagine, labeled with 125I on the tyrosine 0 residue. Sauvagine is a neuropeptide that acts as an agonist at corticotropin-releasing factor receptors (CRF receptors) 1 and 2.
Price Range : 1041.00 USD - 2164.00 USD

Bombesin, [125I]Tyr4

Bombesin, labeled with 125I on the tyrosine 4 residue. Bombesin is an endogenous agonist for bombesin receptors (BB1, BB2, BB3), and is also a tumor marker for certain cancers.
Price Range : 1041.00 USD - 2226.00 USD

Substance P, [125I] Tyr8]

Substance P, labeled with 125I on tyrosine residue 8. Substance-P acts as an antagonist at neurokinin-1 receptors (NK1Rs).
Price Range : 1147.00 USD - 2592.00 USD

CGP 42112A, [125I]

CGP 42112A, labeled with 125I. CGP 42112A acts as an agonist at angiotensin AT2 receptors.
Price Range : 742.00 USD - 1752.00 USD

Thyroxine, ([125I]-T4), Specific Activity: 1080-1320 µCi/µg

Thyroxine (T4) labeled with 125I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T4 detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
Price Range : 764.00 USD - 2513.00 USD

Fractalkine (human, recombinant), 125I

Fractalkine (CX3CL1), labeled with 125I. Fractalkine binds to chemokine receptor CX3CR1, and is involved in the adhesion and migration of leukocytes.
Price Range : 959.00 USD - 2117.00 USD

2`-Deoxycytidine-5`-triphosphate, 5-[125I] iodo-, Tetraammonium Salt

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. 125I dCTP may be used to produce cDNA transcripts of viral or mRNA.
Price Range : 1097.00 USD - 2742.00 USD

Insulin (porcine), Receptor Grade, [125I]TyrA14]

Porcine insulin, labeled with 125I on tyrosineA14. This product is receptor-grade, and was developed for receptor-binding assays. Insulin binds and activates insulin receptor (IR), a tyrosine kinase receptor involved in glucose uptake.
Price Range : 1153.00 USD - 2250.00 USD

Calcitonin [Tyr22] (salmon), [125I] 10 µCi

NEX423 [125I]-Calcitonin, [Tyr22] (s) is suitable for the use in radioimmunoassay as well as in the radio-receptor assay.
List Price : 906.00 USD

Apelin 13 [125I]

Apelin, labeled with 125 I. Apelin is the endogenous ligand for apelin receptors, and is used in receptor binding studies. Apelin 13 is a 13-amino acid peptide corresponding to residues 65-77.
Price Range : 998.00 USD - 3477.00 USD

Adenosine 3',5'-cyclic Phosphoric Acid, 2`-O-succinyl [125I]-Iodotyrosine Methyl Ester

cAMP, labeled with 125I on the tyrosine methyl ester group. I-125 labeled cAMP can be used as a tracer for radioimmunoassays to detect levels of endogenous cAMP in a sample or for GPCR functional assays.
Price Range : 379.00 USD - 4624.00 USD

TGF-β1 (human, recombinant), [125I]

Transforming growth factor beta 1 (TGF-β1), labeled with 125I. TGF-β1 is a cytokine that is involved in cell growth, cell differentiation, and apoptosis.
Price Range : 845.00 USD - 2117.00 USD

Bombesin (6-14), D-Tyr6[125I]

Bombesin (6-14), labeled with 125I. Bombesin binds and activates bombesin receptors BBR1, BBR2, and BBR3, and is a tumor marker for lung cancer, gastric cancer, pancreative cancer, and neuroblastoma.
Price Range : 1269.00 USD - 2385.00 USD

α-MSH, Nle4, D-Phe7, [125I]

α-Melanocyte-stimulating hormone (α-MSH), labeled with 125I. α-MSH is an endogenous hormone that acts as a non-selective full agonist of melanocortin receptors MC1, MC3, MC4, and MC5.
Price Range : 1036.00 USD - 2324.00 USD

Peptide YY (Human), ([125I]-PYY)

Peptide YY, labeled with 125I. Peptide YY acts as a neuropeptide Y receptor Y2 agonist, is released in response to feeding, and is associated with appetite saiety.
Price Range : 892.00 USD - 1999.00 USD

Peptide YY, (Porcine), ([125I]-PYY)

Peptide YY (peptide tyrosine tyrosine), labeled with 125I. Peptide YY acts as a neuropeptide Y receptor Y2 agonist, is released in response to feeding, and is associated with appetite saiety.
Price Range : 1007.00 USD - 2326.00 USD

Thyroxine, ([125I]-T4), Specific Activity: 135-165 µCi/µg

Thyroxine (T4) labeled with 125I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T4 detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available, 4400 Ci/mmol if two labeling sites are available).
Price Range : 651.00 USD - 1816.00 USD

SDF-1α (human, recombinant), [125I]

Stromal cell-derived factor 1 alpha (SDF-1α; CXCL12), labeled with 125I. SDF-1α binds the CXCR4 receptor.
Price Range : 744.00 USD - 1999.00 USD

Ω-Conotoxin MVIIC, [125I]

Ω-Conotoxin MVIIC (ω-Conotoxin MVIIC), labeled with 125I. Ω-Conotoxin MVIIC is a neurotoxin that blocks calcium channels.
Price Range : 743.00 USD - 1951.00 USD

Iodo-Melatonin, 2-[125I]

Melatonin, labeled with 125I. Melatonin binds and activates melatonin receptors, a class of GPCRs that are potential drug targets for circadian rhythm sleep disorders and depression.
Price Range : 988.00 USD - 2498.00 USD

AB-MECA, [125I]-(4-Amino-3-[125I]iodobenzyl-5`-N-)

AB-MECA, labeled with 125I. AB-MECA acts as an agonist at adenosine A3 receptors, a group of GPCRs that are potential drug targets for immune-related disease, including rheumatoid arthritis, cancer, ischaemia, and inflammatory disease.
Price Range : 1190.00 USD - 2319.00 USD

Motilin, [125I]

Motilin, labeled with 125I. Motilin is a peptide hormone that binds motilin receptors, and stimulates contraction of gut smooth muscle.
Price Range : 1153.00 USD - 2319.00 USD

Guanosine 3`,5`-cyclic Phosphoric Acid, 2`-O-succinyl Iodotyrosine Methyl Ester, [125I]

cGMP, labeled with 125I on the tyrosine methyl ester group. I-125 labeled cGMP can be used as a tracer for radioimmunoassays to detect levels of endogenous cGMP in a sample.
Price Range : 379.00 USD - 6000.00 USD

Cholecystokinin Octapeptide, [125I]-, Bolton-Hunter Labeled

Cholecystokinin Octapeptide (CCK-8), labeled with 125I. Cholecystokinin is a neuropeptide that exists in several forms, identified by the number of amino acids in the peptide sequence. CCK8 contains 8 amino acids. The sulphated version of cholecystokinin can bind both Cholecystokinin A and Cholecystokinin B receptors. These receptors are involved in anxiety, feeding, and locomotion and are potential drug targets for depression and satiety.
Price Range : 1028.00 USD - 3536.00 USD

Orexin A, [125I]

Orexin A, labeled with 125I. Orexin A binds to orexin receptors (OX1 and OX2), which are potential drug targets for sleep disorders.
Price Range : 926.00 USD - 1987.00 USD

Vasopressin (Linear), V-1A Antagonist (Phenylacetyl1, 0-Me-D-Tyr2, [125I-Arg6]-)

Vasopressin (linear), labeled with 125I. Linear vasopressin acts as an antagonist at vasopressin receptor 1A (V1AR).
Price Range : 964.00 USD - 2140.00 USD

"Iodinated Compounds" 1-50 of 78 Products and Services