PerkinElmer

Inflammation Research

OF

Inflammation is a natural marker for bodily health, and abnormal inflammatory response is indicated in an increasingly wide net of diseases and disorders, from cardiovascular disease and diabetes to major depression. Detect and quantitate inflammatory biomarkers with our wide range of in vivo, cellular, in situ, and biochemical inflammation research products.

Our products for inflammation research include:

  • LANCE® TR-FRET technology for detection and quantitation of cytokines and other biomarkers
  • AlphaLISA® Immunoassay kits for detection and quantitation of cytokines and other biomarkers
  • DELFIA® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Near-infrared (NIR) fluorescent and chemiluminescent in vivo imaging agents
  • Target-specific radiolabeled ligands and receptor-transfected cell lines and membranes
  • High content screening

This product portfolio meets the demands of many types of inflammation research:

  • Quick and specific detection of inflammatory biomarkers in human and animal samples, including pro-inflammatory cytokines and chemokines like IL-8, IL-6, IL-2, IFN gamma, and TNF alpha and beta.
  • Monitoring acute and pulmonary inflammation and therapeutic treatment in animal models in real time
  • Phenotypic analysis
  • Targeted studies in various sample types with high sensitivity and specificity

Products & Services (327)
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  • Accessories (43)
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Assay Target
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1-25 of 327 Products & Services

  • Opera Phenix High-Content Screening System

    Opera Phenix High-Content Screening System

    The Opera Phenix HCS system has been replaced by the Opera Phenix Plus system.

    Please visit the Opera Phenix Plus webpage.

  • SpectrumBL-CU-Hero

    IVIS® SpectrumBL High-Throughput In Vivo Optical Imaging System

    The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
  • IVIS-SpectrumCT-Hero

    IVIS® SpectrumCT In Vivo Imaging System

    The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
  • FMT In Vivo Imaging Instrument

    FMT 1000 In Vivo Imaging System

    The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
  • IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

    IVIS Lumina XRMS In Vivo Imaging System

    Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina LT In Vivo Imaging System

    The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina III In Vivo Imaging System

    The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
  • Operetta CLS High-Content Analysis System

    Operetta CLS High-Content Analysis System

    Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.
  • Spectrum-CU-Hero

    IVIS Spectrum In Vivo Imaging System

    The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
  • CYR61 (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human cysteine rich angiogenic inducer 61 (CYR61) enables the quantitative determination of human Cyr61 in serum and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 912.00 USD - 17600.00 USD
  • IL-5 (human) Research kits

    The AlphaLISA® Human Interleukin 5 (IL5) Detection Kit is designed for detection and quantitation of human IL5 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 1905.00 USD - 12600.00 USD
  • CCL18 (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human CCL18 enables the quantitative determination of human chemokine (C-C motif) ligand 18 in buffer, human serum, cell media, and PBMC culture supernatant samples using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 939.00 USD - 13300.00 USD
  • AlphaLISA SureFire Ultra Phospho-protein

    Phospho-S6 Ribosomal Protein (Ser235/236) AlphaLISA SureFire Ultra Detection Kit

    The AlphaLISA® SureFire® Ultra p-Ribosomal Protein S6 (Ser235/236) assay is a sandwich immunoassay for quantitative detection of phospho- Ribosomal Protein S6 (phosphorylated on Ser3235/236) in cellular lysates using Alpha Technology.

    Price Range : 526.00 USD - 34900.00 USD
  • VivoTrack-680 Fluorescent Labeling Kit - Standard Kit NEV12000

    VivoTrack 680 NIR Fluorescent Imaging Agent

    Label and track mammalian cells including stem cells, T-cells, macrophages and more with VivoTrack fluorescent labeling dye.

    VivoTrack 680 is an NIR fluorescent lipophilic dye that intercalates in the cell membrane. With high solubility and excellent stability, VivoTrack offers superior brightness and uniform labeling, ideal for cell detection in vitro and longitudinal cell tracking in vivo across many applications including inflammation, immunology, and stem cell research.

    Price Range : 123.00 USD - 310.00 USD
  • Alpha Terbium SureFire Ultra Multiplex MPSU

    Alpha SureFire Ultra Multiplex Phospho (Tyr701)/Total STAT1 Assay Kit

    The AlphaLISA® SureFire® Ultra Multiplex phospho-STAT1 (Tyr701) + Total STAT1 assay kit is used to measure both the phosphorylation of STAT1 and total levels of endogenous STAT1 in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure STAT1 phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.

    Price Range : 946.00 USD - 60600.00 USD
  • AlphaLISA Binding

    TNFα/TNFR2 (human) AlphaLISA Binding Kit

    The AlphaLISA® human TNFα/TNFR2 binding kit is designed for the detection of binding activity between human TNFα and TNFR2, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 2659.00 USD - 13700.00 USD
  • Receptor-expressing cell lines

    Chemokine CCR1, Human Recombinant, CHO-K1 cAMPZen Frozen cells

    Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
    List Price : 682.00 USD
  • LANCE Ultra Biomarker

    IFN-γ (mouse) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Mouse IFN-γ Detection Kit is designed for detection and quantitation of mouse interferon γ in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 903.00 USD - 12000.00 USD
  • In vivo Fluorescent Agents

    FolateRSense 680 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 666.00 USD
  • LANCE Ultra Biomarker

    IL-1α (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human IL-1α Detection Kit is designed for detection and quantitation of human interleuukin-1α in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 903.00 USD - 12000.00 USD
  • LANCE Ultra Biomarker

    TNFα (human) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Human TNFα Detection Kit is designed for detection and quantitation of human TNFα in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 903.00 USD - 12000.00 USD
  • Receptor-expressing cell lines

    AequoZen FroZen Cells, Histamine H1, Human Recombinant, CHO-K1

    Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
    List Price : 1083.00 USD
  • In vivo Fluorescent Agents

    AngioSense Fluorescent Imaging Agent

    In vivo optical imaging of vascular changes and vascular leak is an emerging modality for studying altered physiology in a variety of different cancers and inflammatory states. In oncology, increases in tumor vascular permeability can be an early indicator of tumor angiogenesis. In inflammatory disease increased vascular permeability can indicate alterations in fluid homeostasis in an acute edema response or in chronic organ conditions.

    PerkinElmer’s AngioSense® NIR fluorescent probes are designed to evaluate vascular changes to better understand various disease states or provide valuable information on effects of drug candidates earlier in the development process.

    List Price : 640.00 USD
  • IFN-γ (mouse) AlphaLISA Detection Kit

    The AlphaLISA® Mouse Interferon-γ (IFNγ) Detection Kit is designed for detection and quantitation of mouse IFNγ in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 1905.00 USD - 12600.00 USD
  • IFN-γ (cynomolgus) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for monkey cynomolgus interferon gamma (IFNγ) enables the quantitative determination of cynomolgus IFNγ in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 542.00 USD - 11900.00 USD
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