PerkinElmer

Inflammation Research

OF

Inflammation is a natural marker for bodily health, and abnormal inflammatory response is indicated in an increasingly wide net of diseases and disorders, from cardiovascular disease and diabetes to major depression. Detect and quantitate inflammatory biomarkers with our wide range of in vivo, cellular, in situ, and biochemical inflammation research products.

Our products for inflammation research include:

  • LANCE® TR-FRET technology for detection and quantitation of cytokines and other biomarkers
  • AlphaLISA® Immunoassay kits for detection and quantitation of cytokines and other biomarkers
  • DELFIA® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Near-infrared (NIR) fluorescent and chemiluminescent in vivo imaging agents
  • Target-specific radiolabeled ligands and receptor-transfected cell lines and membranes
  • High content screening

This product portfolio meets the demands of many types of inflammation research:

  • Quick and specific detection of inflammatory biomarkers in human and animal samples, including pro-inflammatory cytokines and chemokines like IL-8, IL-6, IL-2, IFN gamma, and TNF alpha and beta.
  • Monitoring acute and pulmonary inflammation and therapeutic treatment in animal models in real time
  • Phenotypic analysis
  • Targeted studies in various sample types with high sensitivity and specificity

Products & Services (324)
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  • Accessories (43)
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Assay Target
  • CCL1 (1)
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Length
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  • Explorer Kit (1)
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1-25 of 324 Products & Services

  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina LT In Vivo Imaging System

    The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
  • FMT In Vivo Imaging Instrument

    FMT 2000 In Vivo Imaging System

    The FMT 2000 is a workhorse 3D fluorescence tomographic system with the ability to quantitate up to two fluorophores simultaneously.
  • IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

    IVIS Lumina XRMS In Vivo Imaging System

    Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
  • FMT In Vivo Imaging Instrument

    FMT 4000 In Vivo Imaging System

    The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. It comes with four excitation laser channels (635, 680, 750, & 790 nm).
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS® Lumina III In Vivo Imaging System

    The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
  • Spectrum-CU-Hero

    IVIS Spectrum In Vivo Imaging System

    The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
  • FMT In Vivo Imaging Instrument

    FMT 1000 In Vivo Imaging System

    The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
  • Operetta CLS High-Content Analysis System

    Operetta CLS High-Content Analysis System

    Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.
  • Opera Phenix High-Content Screening System

    Opera Phenix High-Content Screening System

    The Opera Phenix HCS system has been replaced by the Opera Phenix Plus system.

    Please visit the Opera Phenix Plus webpage.

  • SpectrumBL-CU-Hero

    IVIS® SpectrumBL High-Throughput In Vivo Optical Imaging System

    The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
  • IVIS-SpectrumCT-Hero

    IVIS® SpectrumCT In Vivo Imaging System

    The IVIS® SpectumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
  • IL-22 (human/rat) AlphaLISA Detection kit

    The AlphaLISA® Human/rat IL-22 Detection Kit is designed for detection and quantitation of human or rat interleukin 22 in cell culture media or serum using a homogeneous (no-wash steps, no separation steps) assay.
    Price Range : 828.00 USD - 12000.00 USD
  • AlphaLISA Binding

    TNFα/TNFR1 (human) AlphaLISA Binding Kit

    The AlphaLISA® human TNFα/TNFR1 binding kit is designed for the detection of binding activity between human TNFα and TNFR1, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 2529.00 USD - 13000.00 USD
  • Periostin (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human periostin enables the quantitative determination of human periostin in buffer, cell culture media, and serum using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 893.00 USD - 12600.00 USD
  • AlphaLISA Binding

    TNFα/TNFR2 (human) AlphaLISA Binding Kit

    The AlphaLISA® human TNFα/TNFR2 binding kit is designed for the detection of binding activity between human TNFα and TNFR2, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
    Price Range : 2529.00 USD - 13000.00 USD
  • Receptor-expressing cell lines

    Histamine H2 AequoScreen cell line

    Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
  • AlphaLISA SureFire Ultra Phospho-protein
    New

    Phospho-PLC G2 (Tyr759) AlphaLISA SureFire Ultra Detection Kit

    The AlphaLISA® SureFire® Ultra p-PLC G2 (Tyr759) assay is a sandwich immunoassay for quantitative detection of phospho-PLC G2 (phosphorylated on Tyr759) in cellular lysates using Alpha Technology.

    Price Range : 526.00 USD - 34900.00 USD
  • LANCE Ultra Biomarker

    CCL2/MCP-1α (mouse) LANCE Ultra TR-FRET Detection Kit

    The LANCE® Ultra Mouse CCL2/MCP-1α Detection Kit is designed for detection and quantitation of mouse Monocyte Chemoattractant Protein 1α in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
    Price Range : 865.00 USD - 11500.00 USD
  • IFN-γ (human) AlphaLISA Biotin-Free Detection Kit

    The AlphaLISA Human IFNγ Biotin-Free Detection Kit is designed for the quantitative detection of human IFNγ in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit uses anti-DIG (anti-Digoxin) Donor beads instead of streptavidin Donor beads, which makes the kit compatible with high-biotin culture media and other sample types that contain high levels biotin (including brain/liver tissue extracts, milk and eggs).
    Price Range : 828.00 USD - 12000.00 USD
  • AlphaLisa Analyte 2

    IFN-γ (ovine), lyophilized (AlphaLISA)

    Ovine IFNγ standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA Ovine IFNγ Detection Kit, but can also be ordered separately.
    List Price : 278.00 USD
  • Membrane Target Systems

    Membrane Target Systems: Histamine H2 (human) membrane preparation, in CHO-K1 cells. 400 Units.

    Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
    List Price : 1036.00 USD
  • Alpha Terbium SureFire Ultra Multiplex MPSU
    New

    Alpha SureFire Ultra Multiplex Phospho (Thr821/826)/Total Rb Assay Kit

    The AlphaLISA® SureFire® Ultra Multiplex phospho-Rb (Thr821/826) + Total Rb assay kit is used to measure both the phosphorylation of Rb and total levels of endogenous Rb in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure Rb phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.

    Price Range : 946.00 USD - 60600.00 USD
  • CCL18 (human) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for human CCL18 enables the quantitative determination of human chemokine (C-C motif) ligand 18 in buffer, human serum, cell media, and PBMC culture supernatant samples using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 893.00 USD - 12600.00 USD
  • AlphaLISA SureFire Ultra Phospho-protein
    New

    Phospho-SLP76 (Tyr145) AlphaLISA SureFire Ultra Detection Kit

    The AlphaLISA® SureFire® Ultra p-SLP76 (Tyr145) assay is a sandwich immunoassay for quantitative detection of phospho-SLP76 (phosphorylated on Tyr145) in cellular lysates using Alpha Technology.

    Price Range : 526.00 USD - 34900.00 USD
  • IFN-γ (cynomolgus) AlphaLISA Detection Kit

    The AlphaLISA® immunoassay kit for monkey cynomolgus interferon gamma (IFNγ) enables the quantitative determination of cynomolgus IFNγ in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
    Price Range : 515.00 USD - 11300.00 USD
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