PerkinElmer

Inflammation Research

OF

Inflammation is a natural marker for bodily health, and abnormal inflammatory response is indicated in an increasingly wide net of diseases and disorders, from cardiovascular disease and diabetes to major depression. Detect and quantitate inflammatory biomarkers with our wide range of in vivo, cellular, in situ, and biochemical inflammation research products.

Our products for inflammation research include:

  • LANCE® TR-FRET technology for detection and quantitation of cytokines and other biomarkers
  • AlphaLISA® Immunoassay kits for detection and quantitation of cytokines and other biomarkers
  • DELFIA® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Near-infrared (NIR) fluorescent and chemiluminescent in vivo imaging agents
  • Target-specific radiolabeled ligands and receptor-transfected cell lines and membranes
  • High content screening

This product portfolio meets the demands of many types of inflammation research:

  • Quick and specific detection of inflammatory biomarkers in human and animal samples, including pro-inflammatory cytokines and chemokines like IL-8, IL-6, IL-2, IFN gamma, and TNF alpha and beta.
  • Monitoring acute and pulmonary inflammation and therapeutic treatment in animal models in real time
  • Phenotypic analysis
  • Targeted studies in various sample types with high sensitivity and specificity

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Product Type
  • Accessories (44)
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Application
  • cAMP (10)
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  • High biotin samples (7)
  • Immunohistochemistry (IHC) (23)
  • In situ hybridization (ISH) (23)
  • In vivo imaging (1)
  • Protein Analysis & Detection (155)
Assay points(200-50,000)
  • 100 (45)
  • 10000 (28)
  • 500 (110)
  • 5000 (80)
Assay Target
  • CCL2 (3)
  • CCL3 (3)
  • CCL4 (1)
  • CCL5 (3)
  • CRP (3)
  • CXCL1 (2)
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  • CXCL10 (3)
  • CXCL12 (2)
  • CXCL4/PF4 (2)
  • CXCL9 (3)
  • Cyr61 (1)
  • Fibrinogen (2)
  • G-CSF (1)
  • GM-CSF (2)
  • HO-1 (2)
  • HO-2 (2)
  • HVEM (2)
  • IFN-λ2 (4)
  • IFNα (2)
  • IFNγ (10)
  • IL-1RA (4)
  • IL-23 (2)
  • IL-23A (2)
  • IL-31 (2)
  • IL-6 (3)
  • IL10 (2)
  • IL11 (2)
  • IL12 (8)
  • IL13 (3)
  • IL15 (1)
  • IL17A (8)
  • IL17F (4)
  • IL18 (1)
  • IL1α (4)
  • IL1β (7)
  • IL2 (4)
  • IL21 (2)
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  • IL25 (4)
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  • IL31 (1)
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  • TNFα (10)
  • TSLP (4)
Assay Target Class
  • Cytokine (137)
  • GPCR (46)
  • Protein (21)
Assay Validated
  • Binding (24)
  • Calcium Fluorescence (7)
  • Calcium Luminescence (19)
  • cAMP (16)
  • Downstream Phosphorylation (7)
  • GTPγS (9)
  • Inositol Phosphate (2)
Automation Compatible
  • Yes (169)
Detection Method
  • Alpha (123)
  • Chromogenic (6)
  • Fluorescence (27)
  • Time-Resolved Fluorescence (TRF) (24)
  • TR-FRET (24)
  • Transmission (2)
Experimental Type
  • In vitro (130)
Fluorescent Agent Type
  • Activatable (9)
  • Cell labeling (2)
  • Targeted (4)
  • Vascular (5)
Fluorophore
  • Coumarin (1)
  • Cy3 (8)
  • Cy5 (4)
  • Fluorescein (6)
  • TMR (5)
Format
  • Microplates (153)
  • Slides (23)
Host Cell
  • CHO-K1 (43)
  • HEK293 (3)
Imaging Modality
  • Chemilumiluminescence (2)
  • Fluorescence (19)
  • High Content (2)
  • microCT Imaging (1)
  • Optical Imaging (9)
Product Brand Name
  • AequoScreen (11)
  • AequoZen (8)
  • AlphaLISA (119)
  • AlphaPlex (4)
  • Ancillary Products (2)
  • cAMPZen (8)
  • Cat B FAST (2)
  • FMT (3)
  • FolateRSense (1)
  • IVIS (6)
  • LANCE Ultra (44)
  • Membrane Target Systems (9)
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  • Operetta CLS (1)
  • ProSense (3)
  • Superhance (1)
  • TSA (12)
  • TSA Plus (12)
  • ValiScreen (10)
  • VivoTrack (2)
  • XenoLight (5)
Receptor Type
  • Anaphylatoxin (1)
  • Bradykinin (4)
  • Chemokine (28)
  • Histamine (11)
  • Prostanoid (2)
Target Species
  • Bovine (6)
  • Cynomolgus (4)
  • Human (115)
  • Monkey (2)
  • Mouse (31)
  • Ovine (2)
  • Porcine (4)
  • Rat (1)
  • Rhesus (2)
Therapeutic Area
  • Angiogenesis (14)
  • Arthritis (16)
  • Atherosclerosis (9)
  • Cancer (2)
  • Cardiovascular (9)
  • Central Nervous System (3)
  • Gastrointestinal (4)
  • Inflammation (216)
  • Metabolic (4)
  • Oncology/Cancer (16)
  • Pain (8)
  • Vascular disease (5)
Volume Capacity
  • 150 µL (2)

"Inflammation" 1-50 of 327 Products and Services

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FMT In Vivo Imaging Instrument

FMT 2000 In Vivo Imaging System

The FMT 2000 is a workhorse 3D fluorescence tomographic system with the ability to quantitate up to two fluorophores simultaneously.

Opera Phenix High-Content Screening System

The Opera Phenix High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
IVIS SpectrumCT 2D/3D Optical/CT In Vivo Imaging System

IVIS SpectrumCT In Vivo Imaging System

The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility and advanced optical feature sets of the IVIS platform integrated with low dose microCT to support longitudinal imaging.
FMT In Vivo Imaging Instrument

FMT 1000 In Vivo Imaging System

The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
IVIS SpectrumBL High Throughput Optical Imaging System

IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
Operetta CLS High Content Analysis Instrument

Operetta CLS High-Content Analysis System

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.
IVIS SpectrumBL High Throughput Optical Imaging System

IVIS Spectrum In Vivo Imaging System

The IVIS® Spectrum in vivo imaging system uses a novel patented optical imaging technology to facilitate non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina III In Vivo Imaging System

The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
FMT In Vivo Imaging Instrument

FMT 4000 In Vivo Imaging System

The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. It comes with four excitation laser channels (635, 680, 750, & 790 nm).
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina LT In Vivo Imaging System

The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

IVIS Lumina XRMS In Vivo Imaging System

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
RediJect COX-2 Probe Standard Kit 133314

RediJect COX-2 Fluorescent Imaging Probe (Standard kit)

XenoLight RediJect COX-2 is a a novel fluorescent imaging probe for pre-clinical research that specifically detects the cyclooxygenase-2 (COX-2) biomarker noninvasively in vivo as well as in ex vivo tissue analysis applications. 
List Price : 543.00 USD
RediJect COX-2 Probe Explorer Kit 133316

RediJect COX-2 Fluorescent Imaging Probe (Explorer kit)

XenoLight RediJect COX-2 is a a novel fluorescent imaging probe for pre-clinical research that specifically detects the cyclooxygenase-2 (COX-2) biomarker noninvasively in vivo as well as in ex vivo tissue analysis applications. 
List Price : 181.00 USD
Protein

IL-12/p40 (human), lyophilized (LANCE)

Human IL-12/p40 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human IL-12/p40 Detection Kit, but can also be ordered separately.
List Price : 240.00 USD
AlphaLISA immunoassay kits

C-Reactive Protein (human) AlphaLISA Detection Kit

The AlphaLISA® Human C-Reactive Protein (CRP) Detection Kit is designed for detection and quantitation of human CRP in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1520.00 USD - 10100.00 USD
AlphaLisa Analyte 2

IL-31 (human), lyophilized (LANCE)

Human IL-31 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human IL-31 TR-FRET Detection Kit, but can also be ordered separately.
List Price : 233.00 USD
AlphaLisa Analyte 2

TSLP (mouse), lyophilized (AlphaLISA)

Mouse Thymic stromal lymphopoietin (TSLP) standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA mouse TSLP Detection Kit, but can also be ordered separately.
List Price : 295.00 USD

IL-1α (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-1α Detection Kit is designed for detection and quantitation of human interleuukin-1α in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 796.00 USD - 10600.00 USD

IL-31 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-31 Detection Kit is designed for detection and quantitation of human interleukin-31 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 773.00 USD - 10300.00 USD
AlphaLISA immunoassay kits

IL-13 (mouse) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for mouse IL-13 enables the quantitative determination of mouse interleukin-13 in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 600.00 USD - 14400.00 USD
LANCE Detection Kit

IL17F (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-17F Detection Kit is designed for detection and quantitation of human interleukin 17 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 796.00 USD - 10600.00 USD

IL-1β (mouse) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Mouse IL-1β Detection Kit is designed for detection and quantitation of mouse interleukin 1β in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 796.00 USD - 10600.00 USD
AlphaLisa Analyte 2

CXCL12/SDF-1 (human), liquid (AlphaLISA)

Human CXCL12 (SDF-1) standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human CXCL12 Detection Kit, but can also be ordered separately.
List Price : 233.00 USD
LANCE Detection Kit

IL-4 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-4 Detection Kit is designed for detection and quantitation of human interleukin 4 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 796.00 USD - 10600.00 USD
Receptor-expressing cell lines

ValiScreen Histamine H1 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
AlphaLISA immunoassay kits

IL-22 (human/rat) AlphaLISA Detection kit

AlphaLISA no-wash immunoassay kit for detection and quantitation of human or rat IL-22 in serum, cell culture supernatants, and other samples.
Price Range : 695.00 USD - 10000.00 USD
alphaimmunoassay1

IL-1β (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin-1β (IL1β) Detection Kit is designed for detection and quantitation of human IL-1β in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1520.00 USD - 10100.00 USD
alphaimmunoassay1

G-CSF (human) AlphaLISA Detection Kit

The AlphaLISA® Human Granulocyte Colony-Stimulating Factor (G-CSF) Detection Kit is designed for detection and quantitation of human G-CSF in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.

Price Range : 1520.00 USD - 10100.00 USD
Protein

IL17F (human), lyophilized (LANCE)

Human interleukin 17 (IL-17F) standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human IL-17F Detection Kit, but can also be ordered separately.
List Price : 240.00 USD
Receptor-expressing cell lines

AequoZen FroZen Cells, Chemokine CCR6, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 961.00 USD
PerkinElmer

CXCL9/MIG (human), lyophilized (LANCE)

Human CXCL9 standard, lyophilized, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra human CXCL9/MIG Detection Kit, but can be ordered separately.
List Price : 240.00 USD
AlphaPlex Terbium immunoassay kits

AlphaPlex-545 Human IL17 Detection Kit

The AlphaPlex™ 545 (Terbium) Human IL17 Detection Kit is designed for the quantitative determination of human IL17 together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous (no wash steps, no separation steps) assay.
Price Range : 359.00 USD - 10000.00 USD
In vivo Fluorescent Agents

ProSense 750 EX Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
List Price : 618.00 USD
alphaimmunoassay1

GM-CSF (human) AlphaLISA Detection Kit

The AlphaLISA® Human Granulocyte/Macrophage Colony-Stimulating Factor (GM-CSF) Detection Kit is designed for detection and quantitation of human GM-CSF in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1520.00 USD - 10100.00 USD
AlphaLISA immunoassay kits

IL-33 (mouse) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for mouse IL-33 enables the quantitative determination of mouse interleukin-33 in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 600.00 USD - 14400.00 USD
AlphaLISA assay principle

IL-31 (Human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for IL-31 enables the quantitative determination of human IL-31 in serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows no cross-reactivity with mouse IL31. Cross-reactivity with other species has not been tested.
Price Range : 618.00 USD - 18500.00 USD
AlphaLISA immunoassay kits

IL-12 (bovine) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for bovine IL-12 enables the quantitative determination of bovine IL-12 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 600.00 USD - 18000.00 USD
AlphaLisa Analyte 2

IL-17F (human) Iyophilized (AlphaLISA)

Human IL17F standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA IL17F Detection Kit, but can be ordered separately.
List Price : 304.00 USD

IFN-γ (mouse) AlphaLISA Detection Kit

The AlphaLISA® Mouse Interferon-γ (IFNγ) Detection Kit is designed for detection and quantitation of mouse IFNγ in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1520.00 USD - 10100.00 USD

CCL4/MIP-1ß (human) AlphaLISA Detection Kit

The AlphaLISA® Human C-C Motif Chemokine 4 / Macrophage Inflammatory Protein-1beta (CCL4 / MIP-1ß) Detection Kit is designed for detection and quantitation of human CCL4/MIP-1ß in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1624.00 USD - 10100.00 USD
PerkinElmer

TSA Plus Biotin

TSA® Plus Biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 368.00 USD - 1380.00 USD

IL-10 (mouse) AlphaLISA Detection Kit

The AlphaLISA® Mouse Interleukin-10 (IL-10) Detection Kit is designed for detection and quantitation of mouse IL-10 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1520.00 USD - 10100.00 USD
Receptor-expressing cell lines

cAMPZen Frozen cells, Chemokine CXCR2, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 606.00 USD
PerkinElmer

Membrane Target Systems: Histamine H1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 936.00 USD

Monocyte Chemoattractant Protein-1 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Monocyte Chemoattractant Protein-1 (CCL2 / MCP1) Detection Kit is designed for detection and quantitation of human CCL2/MCP1 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1520.00 USD - 10100.00 USD
AlphaLISA immunoassay kits

IL-1α (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin 1 alpha (IL1α) Detection Kit is designed for detection and quantitation of human IL1α in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1624.00 USD - 10100.00 USD

CCL2/MCP-1α (mouse) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Mouse CCL2/MCP-1α Detection Kit is designed for detection and quantitation of mouse Monocyte Chemoattractant Protein 1α in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 796.00 USD - 10600.00 USD
AlphaLISA immunoassay kits

IL-11 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin 11 (IL-11) Detection Kit is designed for detection and quantitation of IL-11 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1520.00 USD - 10100.00 USD
LANCE Detection Kit

IFN-λ2 (human) LANCE TR-FRET Detection Kit

The LANCE® Ultra Human IFN-λ2 Detection Kit is designed for detection and quantitation of human interferon λ2 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 1557.00 USD - 10600.00 USD
Receptor-expressing cell lines

AequoZen FroZen cells, Chemokine CCR9a, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 961.00 USD

"Inflammation" 1-50 of 327 Products and Services

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