PerkinElmer

Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

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When your mass spectrometry analyses involve inorganic trace-elemental detection, we have an ICP-MS solution for your needs. Our state-of-the-art ICP-MS systems offer a range of interference-removal techniques to meet all analyses -- from high-throughput samples with few interferences to samples that require the removal of unknown interferences or applications demanding the best performance with the lowest detection limits. We have been at the forefront of inorganic analytical technology for over 50 years and understand the unique and varied needs of the customers and markets we serve.

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1-12 of 411 Products & Services

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  • NexION 2000 ICP-MS

    NexION 2000 ICP Mass Spectrometer

    PerkinElmer’s NexION® 2000 is the most versatile ICP-MS on the market, featuring an array of unique technologies that combine to deliver the highest performance no matter what your analytical challenge. Discover the effortless versatility of an instrument that makes it easy to handle any sample matrix, any interference, and any particle size.

    PerkinElmer received on April 11, 2018 the Application Award from LaborPraxis in the category Bio and Pharma Analysis for the NexION 2000 ICP-MS. We were awarded this prize during analytica 2018 in Munich, Germany, in acknowledgment of a new technique enabling users to quantify the amount of metal in an individual cell for the first time.
  • NexION 1000B ICP-MS

    NexION 1000 ICP Mass Spectrometer

    The NexION® 1000 ICP-MS is the ideal high-throughput system for routine, multi-elemental, trace-level analyses that meet regulatory standards – and that works within your budget. It features a host of proprietary technologies that combine to deliver exceptional speed and operational simplicity, making your lab more efficient than ever before.
  • PFA Microflow Nebulizer with Ultem Probe

    PFA-50 MicroFlow Nebulizer with Integrated Autosampler Probe and Ultem Support

    This PFA MicroFlow Nebulizer with Integrated Autosampler Probe is for Avio® and Optima® ICP-OES series instruments, as well as NexION® 300/350 ICP-MS series instruments. These nebulizers self-aspirate at low flow rates with any autosampler and provide the same benefits of the PFA MicroFlow nebulizer. MicroFlow nebulizers are resistant to clogging, reliably self-aspirated or pumped to produce a fine aerosol for high transport efficiency and high sensitivity. The integrated sampling probe is constructed by encapsulating a rigid support material between layers of PFA to provide a chemically-resistant probe that is mechanically stable and resilient.

    List Price : 2225.00 USD
  • Liquid Fitting for MEINHARD Plus Nebulizers

    This Nebulizer Liquid Fitting is designed for use with MEINHARD Plus nebulizers in PerkinElmer ICP-MS instruments.

    List Price : 48.00 USD
  • Multi-use Quartz Window

    Replacement Quartz Windows for Sample Holder Cover for DSC DPA 7, FIAS 100/400/400MS, FIAS 200, Graphite Furnace and Flow Injection Mercury System (FIMS).
    List Price : 27.00 USD
  • List Price : 18.00 USD
  • PFA Microflow Nebulizer with Ultem Probe

    PFA-100 MicroFlow Nebulizer with Integrated Autosampler Probe and Ultem Support

    This PFA MicroFlow Nebulizer with Integrated Autosampler Probe is for Avio® and Optima® ICP-OES series instruments, as well as NexION® 300/350 ICP-MS series instruments. These nebulizers self-aspirate at low flow rates with any autosampler and provide the same benefits of the PFA MicroFlow nebulizer. MicroFlow nebulizers are resistant to clogging, reliably self-aspirated or pumped to produce a fine aerosol for high transport efficiency and high sensitivity. The integrated sampling probe is constructed by encapsulating a rigid support material between layers of PFA to provide a chemically-resistant probe that is mechanically stable and resilient.

    List Price : 2039.00 USD
  • Black/Black 0.76mm i.d. PVC Peristaltic Pump Tubing pkg.12

    We offer a wide range of high-quality peristaltic pump tubing for all of your ICP-OES and ICP-MS applications. Remember to replace your tubing frequently and always keep spares on hand.
    List Price : 23.00 USD
  • Female CTFE Liquid Fitting

    Female Barb CTFE Fitting

    This female CTFE Liquid Fitting, recommended for low pressure applications, is for use with NexION® 300/350/1000/2000 ICP-MS instruments.

    List Price : 60.00 USD
  • Adapter F, 1/4in (6.4 mm) Internal Screw Thread, 0.7mm Outer Diameter Pt/Ir Capillary Nipple for FIAS-100, FIAS-400, FIAS-400MS and FIAS-200

    The use of flow injection saves time, money and manpower – while at the same time, extending your analytical flexibility and capabilities.
    List Price : 71.00 USD
  • PFA MicroFlow Nebulizer for NexION

    PFA MicroFlow Nebulizer with Integrated Capillary, 200 μL/min

    This PFA Nebulizer with Integrated Fluoropolymer Capillary is for Avio® and Optima® ICP-OES series instruments, as well as NexION® 300/350 ICP-MS series instruments. Self-aspirating PFA MicroFlow nebulizers are constructed entirely from chemically resistant fluoropolymers ideal for strong acids, alkalis, organics and high-salt solutions. They are resistant to clogging and produce a fine aerosol for high transport efficiency and high sensitivity.

    List Price : 1767.00 USD
  • Antifoaming Silicone Emulsion, Dow Corning DB 110 A, 500mL

    Controls foaming during reaction when using the MHS-10 or MHS-20.
    List Price : 122.00 USD
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Business Insights (12)
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1-12 of 12 Business Insights

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  • Application Note

    Testing and Validation of Various Antacids for Elemental Impurities using the NexION 2000 ICP-MS

    The United States Pharmacopeia (USP) has announced that its new standards for elemental impurities in drug products has been implemented since January 1, 2018. General Chapters <232> and <2232> specify the list of elements and their permissible daily exposure (PDE) limits based on the route of administration.

  • Application Note

    Analysis of Soils and Waters in Accordance with U.S. EPA Method 6020B using the NexION 2000 ICP-MS

    Through the years, both industry and analytical instrumentation have advanced. With the development of new chemicals and processes, new pollutants may enter the environment. However, the capabilities of analytical instruments have also increased, allowing the measurement of ever lower levels of environmental contaminants, as well as new pollutants.

  • Application Note

    Accurate Sizing and Precise Counting of 10 nm Gold Nanoparticles using the NexION 2000 ICP-MS

    In this work, we demonstrate that PerkinElmer's NexION® 2000 ICP-MS, with its unique RF generator and ion optics, coupled with the Syngistix™ Nano Application Software Module, can be used to accurately measure and characterize NP sizes of 10 nm and smaller, both alone and in a mixture of NPs of various sizes.

  • Application Note

    New Research Evaluating Cisplatin Uptake in Ovarian Cancer Cells by Single Cell ICP-MS

    Cisplatin, carboplatin, and oxaliplatin are the most widely used of platinum-based cancer chemotherapy drugs in the Western world. Cisplatin's effectiveness is due to its ability to bind to the DNA, resulting in DNA-platinum (Pt) adducts, which bend the DNA. The cells must then repair the DNA damage, otherwise DNA replication is blocked resulting in cell death. Many cancers are initially sensitive to platinum-based treatment, but patients frequently relapse with tumors displaying resistance to further cisplatin therapy.

  • Application Note

    Transport of Nanoparticles From Coated Surfaces Through Physical Contact

    This work investigated the transfer of Ag and CuO nanoparticles from consumer products via simulated dermal contact by using textile wipes as a surrogate using PerkinElmer’s NexION ICP-MS single particle analyzer with the unique Syngistix Nano Application software module for data collection and analysis

  • Application Note

    Analysis of Cerium Dioxide Nanoparticles in Soil Using Single Particle ICP-MS

    This work demonstrates a robust method using SP-ICP-MS technology to detect CeO2 NPs which were extracted from soil samples with tetrasodium pyrophosphate (TSPP). Over the past few decades, engineered nanoparticles (ENPs) have been increasingly used in many commercial products. As a result, more and more ENPs have been released into the environment, which raises concerns over their fate, toxicity and transport therein.

  • Application Note

    Analysis of Drinking and Natural Waters using the NexION 2000 ICP-MS

    This work has demonstrated the ability of the NexION 2000 ICP-MS to analyze both natural and drinking water samples in Standard (i.e. non-cell) mode, in accordance with U.S. EPA Method 200.8. Accuracy has been demonstrated through the analysis of several reference materials and spike recoveries, with stability of at least nine hours. Method detection limits allow for trace-level determinations, while the ability to selectively suppress user-defined isotopes also allows the measurement of analyte levels usually only possible by ICP-OES or Flame AA. The NexION 2000 provides a comprehensive solution to the challenge of U.S. EPA Method 200.8 and other drinking and natural water analytical requirements across the globe.

  • Application Note

    Fast Digestion Analysis of Lead and Cadmium in Rice Using GFAAS with Deuterium Background Correction

    Toxic elements, such as lead (Pb) and cadmium (Cd), are entering the food chain through environmental contamination. Rice, as the most widely consumed cereal grain in Asia, can quickly pick up Pb and Cd from soil, thereby seriously endangering human health through diet. These toxic element levels need to be carefully monitored. Maximum levels of Pb and Cd are strictly regulated in Asian countries, especially in China; therefore, it is extremely important to develop a simple, reliable method for trace levels of Pb and Cd in rice. The allowable maximum levels of Pb and Cd in grains in EU and China are required to be below 0.2 mg/kg (Commission Regulation EC 1881/2006 and Chinese GB 2715-2016 Hygienic Standard). Graphite furnace atomic absorption spectroscopy (GFAAS) is the officially recommended technique for detection of trace elements in various food stuffs (GB/T 5009.15-2017, GB/T 5009. 12-2017 and EN 14083:2003). Food samples are usually pretreated before GFAAS analysis using various methods: microwave digestion, hot block digestion, dry ashing, and hot plate digestion. These conventional digestion procedures are usually complicated and time-consuming (2-4 hours or longer). Plus, they require large quantities of corrosive and oxidizing reagents, increasing the chance for contamination which could lead to inaccurate results. However, fast digestion can effectively speed up the sample preparation procedure while reducing the use of corrosive reagents and the chance for contamination.

  • Application Note

    Analysis of Single-Walled Carbon Nanotubes with SP-ICP-MS

    Measuring the amount of metals in CNTs presents a challenge. High levels can be measured directly in the solid by several techniques, including XRF and TEM, while low-level analysis requires complete digestion of the sample prior to analysis by ICP-OES or ICP-MS.

  • Application Note

    Characterization of TiO2 Nanoparticle Release from Fabrics By Single Particle ICP-MS

    In the textile industry, the use of titanium dioxide (TiO2) nanoparticles (NPs) is increasing due to their ability to provide UV protection, increase the hydrophilic nature of fabrics, provide antibacterial characteristics, and reduce odors. This work studies the release of TiO2 NPs from various commercial textile products which do not advertise that TiO2 NPs have been added.

  • Application Note

    Fast Digestion Analysis of Lead and Cadmium in Rice Using Graphite Furnace Atomic Absorption

    Lead (Pb) and cadmium (Cd) are common pollutants in grains and are extremely toxic. Pb is harmful to human organs even at trace levels, and once it accumulates in the body, it causes inhibition of hemoglobin formation and neurological disorders. Cd is even classified as human carcinogen [Group 1 - according to International Agency for Research on Cancer]. It is reported that Cd leads to severe kidney problems which can be fatal and is also associated with brittle bones and liver problems. Rice, as the most widely consumed cereal grain in Asia/China, can quickly pick up Pb and Cd from toxins, pesticides and fertilizers in the soil, thereby endangering the health of millions of people through their diet. Therefore, it is extremely important to develop a simple, reliable method to monitor the levels of Pb and Cd in rice. According to Chinese national standard GB 2715-2016 Hygienic Standard for Grain, the maximum concentrations of Pb or Cd in grains must be below 0.2 mg/kg; the allowable level in the European Union is the same [EC 1881/2006]. The official technique for the determination of heavy metals in both cases is graphite furnace atomic absorption spectroscopy (GFAAS, GB/T 5009. 12-2017, GB/T 5009-2017. 15 and EN 14083:2003). Samples can be pretreated using various methods, including microwave digestion, hot block digestion, dry ashing, and hot plate digestion. It is found that these conventional digestion procedures are always complicated and time-consuming (two-four hours or even longer). Plus, conventional sample preparation techniques require large quantities of corrosive and oxidizing reagents, increasing the chance for contamination which could lead to inaccurate results. Special PTFE vessels are needed for microwave digestion; however, reusable utensils might also cause cross contamination.

  • Application Note

    Quantification of Nanoparticle Uptake into Cancer Cells using Single Cell ICP-MS

    Nanoparticles (NPs) have been of significant interest over the last two decades as they offer attractive benefits for drug delivery to overcome limitations in conventional chemotherapy. Nanoparticles can be engineered to carry both drugs and imaging probes to simultaneously detect and treat cancer. They may also be designed to specifically target diseased tissues and cells in the body. A number of nanoparticlebased cancer therapeutics have been approved for clinical use and/or are currently under development.