PerkinElmer

High Throughput and Phenotypic Screening

OF

Complete solutions for high-throughput and phenotypic screening – together, this spells discovery.

To get drugs to market that much sooner, you need to accelerate your workflow, upstream and downstream. Our screening solutions are a crucial component in that effort: State-of-the art imaging and detection instruments, assay technologies, reagents, versatile automation systems, and powerful informatics solutions working together to ensure consistent, accurate, physiologically relevant results – with one-of-a-kind analytics to wrest more meaning from your findings. Amplify your phenotypic or target-based screens to identify hits and lead compounds in small and focused or high-throughput volumes by using of complete suite of instrument, reagents and informatics solutions:

  • Screening assays for molecular targets
  • High content screening using cellular models
  • High content analysis of microtissues and 3D cell culture
  • Orthogonal testing and secondary screening
  • Selectivity screening
  • Large volume data capture and rapid analysis

High Throughput Screening
High Throughput Screening

High Throughput Screening

From validated assays to verified workflows, our HTS solutions for target-based screening enhance efficiency in your lab and confidence in your results.
Screening Data Analysis
Screening Data Analysis

Data Analysis

With the large volumes of data generated by high-throughput and phenotypic screening, you need software solutions that can aggregate and interpret your results. We offer scalable platforms that make it easy to access and manage all relevant data for enhancing the speed and efficiency in drug discovery.

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EnVision_Alone_Left_Angle

EnVision 2105 Multimode Plate Reader

The EnVision 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

The EnVision 2105 model delivers even higher sensitivity for time-resolved fluorescence (TRF) applications, and the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP). In addition, the Alpha 775 laser module is designed for plant assays.

JANUS G3 Varispan Automated Workstation

JANUS G3 Varispan Automated Workstation

The JANUS® G3 Automated Workstation offers multiple pipetting technologies on a single instrument platform. The instrument consists of a modular platform that expands with flexible 4- or 8-tip Varispan arm, providing an automated liquid handling solution with flexibility in throughput, plate capacity, and dynamic volume range.
VictorX_ImageA_320px

VICTOR Multilabel Plate Reader

The VICTOR Multilabel plate reader has been replaced by the VICTOR Nivo multimode plate reader. Please contact your local representative for further information, or visit the VICTOR Nivo product page (Part Number - HH35000500).
JANUS-G3-Standard-8Tip-Varispan-and-MDT-Workstation

JANUS G3 Varispan MDT Automated Workstation

The JANUS® G3 Automated Workstation offers multiple pipetting technologies on a single instrument platform. The instrument consists of a modular platform and combines a flexible 4- or 8-tip Varispan™ arm with 96- or 384-channel Modular Dispense Technology™ (MDT) dispense head, providing an automated liquid handling solution with flexibility in throughput, plate capacity, and dynamic volume range.

ViewLux uHTS Microplate Imager

The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.

The ViewLux uHTS microplate imager is available outside the EU. Please contact your local representative to discuss alternative products.

Opera Phenix High-Content Screening System

The Opera Phenix High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
Janus-MDT-Only-Alpha_320px

JANUS G3 MDT Automated Workstation

The JANUS® G3 MDT Automated Workstation offers multiple pipetting technologies on a single instrument platform. The instrument consists of an expanding modular platform and a 96- or 384-channel Modular Dispense Technology (MDT) dispense head, and provides an automated liquid handling solution with flexibility in throughput, plate capacity, and dynamic volume range.
EnSight multimode plate-reader

EnSight Multimode Plate Reader

The EnSight multimode plate reader combines labeled, label-free* & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.

*Label free detection module of EnSight Plate Reader is available outside the EU. Please contact your local representative for further details.

JANUS G3 Btx Pro-Plus

JANUS G3 BioTx Pro Plus Workstation

The JANUS® G3 Bio Tx Pro Plus offers full walk-away automation for high-throughput process development, enabling more data from precious starting materials and limited resources.

EnSpire Multimode Plate Reader

EnSpire® Multimode Plate Reader is designed to meet the demands of multi-user research environments, providing high performance technology and flexibility for a range of applications without compromising sensitivity. Combine this with our expertise and portfolio of reagents, PerkinElmer offers an unrivaled solution to your application needs.

EnSpire Plate Reader is available outside the EU. Please contact your local representative for further details.

EnSpire Alpha Plate Reader

The EnSpire Alpha Plate Reader provides proven Alpha technology to your lab at an affordable price and from the Alpha detection leader.

EnSpire Plate Reader is available outside the EU. Please contact your local representative for further details.

AlphaLISA immunoassay kits

Aβ 1-40 (human) High Specificity AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human Aβ40 enables the detection and quantitation of human Aβ40 in human cerebrospinal fluid and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows negligible cross-reactivity with other forms of Amyloid beta (i.e. Aβ1-38 and Aβ1-42).
Price Range : 2827.00 USD - 22100.00 USD
alphascreen surefire total

AlphaScreen SureFire Total Akt1 research kit

The AlphaScreen® SureFire® Akt 1 (total) assay is a sandwich immunoassay for quantitative detection of Akt 1 in cellular lysates using Alpha Technology. The assay is an ideal system for normalizing Akt levels for experiments measuring changes in Akt phosphorylation.
Price Range : 1653.00 USD - 17700.00 USD
AlphaLisa Analyte 2

Aβ 1-40 (human), lyophilized (AlphaLISA)

Human Aβ 1-40 standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human Aβ 1-40 Detection Kit, but can be ordered separately.
List Price : 240.00 USD
alphascreen surefire total

AlphaScreen SureFire Total IkB alpha Assay Kit

The AlphaScreen® SureFire® total p70 S6K assay is a sandwich immunoassay for quantitative detection of p70 S6K (both phosphorylated and non-phosphorylated) in cellular lysates using Alpha Technology. This assay is intended to be used as a normalization for phosphorylation studies.
Price Range : 1493.00 USD - 16100.00 USD
AlphaLISA immunoassay kits

E-Cadherin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human E-cadherin enables the detection and quantitation of human E-cadherin in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 446.00 USD - 9700.00 USD
AlphaLISA SureFire Ultra kits

AlphaLISA SureFire Ultra Total ERK 1/2 Assay Kit

The AlphaLISA® SureFire® Ultra™ Total ERK 1/2 assay is a sandwich immunoassay for quantitative detection of ERK 1/2 (both phosphorylated and non-phosphorylated) in cellular lysates using Alpha Technology. This assay is intended to be used as a normalization for phosphorylation studies.
Price Range : 489.00 USD - 28400.00 USD

SpectraPlate (384-well, clear, sterile and TC-treated)

384-well transparent tissue-culture treated (TC-treated) microplate for cell-based absorbance (colorimetric) assays.
Price Range : 204.00 USD - 680.00 USD
PerkinElmer

Leptin (mouse), lyophilized (LANCE)

Mouse leptin standard, lyophilized, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Mouse Leptin Detection Kit, but can be ordered separately.
List Price : 240.00 USD

AlphaScreen Phosphotyrosine (PT66) Assay Kit

AlphaScreen phosphoprotein kits are designed to detection phosphoproteins in biochemical or cellular kinase assays. This kit contains streptavidin Donor beads and AlphaScreen Acceptor beads conjugated with the antiphosphotyrosine PT66 antibody. This kit can be used to capture biotinylated phosphoproteins, biotinylated phosphorylated peptides, or biotinylated antibodies in complex with phosphorylated proteins.
Price Range : 227.00 USD - 13800.00 USD
PerkinElmer

LANCE Ultra Europium-anti-phospho-Acetyl-CoA Carboxylase (Ser79) Antibody

Mouse monoclonal antibody labeled with the LANCE® Europium W-1024-ITC chelate. This antibody detects peptides derived from rat Acetyl-CoA Carboxylase phosphorylated at Ser79. Acetyl-CoA Carboxylase peptides can be phosphorylated by the AMPKα1 kinase. Sequence motif recognized: SSM-pS-GL
Price Range : 2043.00 USD - 7100.00 USD
AlphaLISA immunoassay kits

BMP-7 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human BMP-7 enables the detection and quantitation of human BMP-7 in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 446.00 USD - 9700.00 USD

StorPlate-96U, Polypropylene, 96 well, round bottom, (U)

Polypropylene 96-well round U-bottom plates for compound storage.
Price Range : 140.00 USD - 591.00 USD
Receptor-expressing cell lines

AequoZen Frozen cells, Vasopressin V1B, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 961.00 USD
LANCE Detection Kit

VEGF (mouse) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Mouse VEGF-A Detection Kit is designed for detection and quantitation of human CXCL1/GRO-α in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 796.00 USD - 10600.00 USD

SpectraPlate-1536 TC, Clear, sterile, TC treated, Case of 50

1536-well transparent TC-treated microplate for cell-based absorbance (colorimetric) assays.
List Price : 1170.00 USD
SureFire principle

AlphaScreen SureFire ATF1 (p-Ser63) Assay Kit

The AlphaScreen® SureFire® p-ATF1 (Ser63) assay is a sandwich immunoassay for quantitative detection of phospho-ATF1 (phosphorylated on Ser63) in cellular lysates using Alpha Technology.
Price Range : 1493.00 USD - 16100.00 USD
AlphaLisa Analyte 2

Alpha-1 Anti-Trypsin (A1AT) (human), lyophilized (AlphaLISA)

Human A1AT standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human A1AT Detection Kit, but can be ordered separately.
List Price : 240.00 USD
AlphaLISA immunoassay kits

IL-33 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human IL-33 enables the quantitative determination of human interleukin-33 in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 600.00 USD - 14400.00 USD
alphascreen surefire total

Total ERK (monoclonal) AlphaScreen SureFire Assay Kit

The AlphaScreen® SureFire® total ERK assay is a sandwich immunoassay for quantitative detection of ERK (both phosphorylated and non-phosphorylated) in cellular lysates using Alpha Technology. This assay is intended to be used as a normalization for phosphorylation studies. This assay performs similarly to the TGRTES SureFire kit, but contains a monoclonal antibody for ERK detection.
Price Range : 492.00 USD - 17700.00 USD
AlphaLISA SureFire Ultra kits

AlphaLISA SureFire Ultra p-ERK1/2 (Thr202/Tyr204) Assay Kit

The AlphaLISA® SureFire® Ultra p-ERK 1/2 (Thr202/Tyr204) assay is a sandwich immunoassay for quantitative detection of phospho-ERK 1/2 (phosphorylated on Thr202/Tyr204 in ERK1, or Thr185/Tyr187 in ERK2) in cellular lysates using Alpha Technology.
Price Range : 489.00 USD - 28400.00 USD
alphascreen surefire total

AlphaScreen SureFire ALK Total Assay Kit

The AlphaScreen® SureFire® ALK (total) assay is a sandwich immunoassay for quantitative detection of ALK in cellular lysates using Alpha Technology. The assay is an ideal system for normalizing Akt levels for experiments measuring changes in ALK phosphorylation.
Price Range : 1493.00 USD - 16100.00 USD

AlphaScreen GST Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-GST conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
Price Range : 180.00 USD - 13800.00 USD
LANCE Detection Kit

c-Myc (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra c-Myc Detection Kit is designed for detection and quantitation of c-Myc peptide tag in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 796.00 USD - 10600.00 USD
PerkinElmer

LANCE Ultra Europium-anti-phospho-Histone H3 (Ser10) Antibody

Mouse monoclonal antibody labeled with the LANCE Europium W-1024-ITC chelate. This antibody detects peptides derived from Histone H3 phosphorylated by Ser10. Histone H3 peptides can be phosphorylated by several kinases, including Aurora B. Sequence motif recognized: ARTKQTARKSTGGKAPRKQLAGCG
Price Range : 2043.00 USD - 7100.00 USD
Alpha_Donor_bead_1

Alpha Glutathione Donor beads

Alpha Donor beads coated with glutathione.
Price Range : 503.00 USD - 9400.00 USD
AlphaLISA SureFire Ultra kits

AlphaLISA SureFire Ultra Total GAPDH Assay Kit

The AlphaLISA® SureFire® Ultra™ Total GAPDH assay is a sandwich immunoassay for quantitative detection of GAPDH in cellular lysates using Alpha Technology. This assay is intended to be used as a normalization for cell number.
Price Range : 489.00 USD - 28400.00 USD
Assay principle of Alpha Terbium SureFire Ultra assay

Phospho-4E-BP1 (Thr37/46) Terbium SureFire Ultra Detection Kit

The Alpha SureFire® Ultra™ Multiplex kits allow the rapid, sensitive, and quantitative detection of two phosphoprotein targets in each well of an assay plate. This kit can be used in combination with any AlphaLISA SureFire Ultra assay to detect phospho-4E-BP1 (Thr37/46) in a multiplexed assay.
Price Range : 367.00 USD - 22100.00 USD

ViewPlate (384-well, black with clear bottom, PDL-coated, TC-treated, sterile)

384-well tissue culture treated (TC-treated), poly-D-lysine (PDL) coated ViewPlate microplate with clear bottom and black well walls for high content analysis and other cell-based applications.
Price Range : 884.00 USD - 3301.00 USD
AlphaLISA immunoassay kits

IgA (bovine) AlphaLISA Detection Kit

The AlphaLISA immunoassay kit for detection and quantitation of bovine IgA in serum, cell culture supernatants, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
Price Range : 645.00 USD - 10300.00 USD
DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

DELFIA Eu-N1 Streptavidin

DELFIA® Europium-labeled streptavidin, for use in DELFIA time-resolved fluorescence (TRF) assays.
List Price : 380.00 USD
Receptor-expressing cell lines

cAMPZen FroZen Cells, Vasopressin V2, Human Recombinant, 1321N1.

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 606.00 USD
Protein

Chorionic gonadotropin (human), lyophilized (LANCE)

Human chorionic gonadotropin (hCG) standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra hCG Detection Kit, but can also be ordered separately.
List Price : 295.00 USD

Lid with spacers (for improved airflow). Black, sterile. 200/PK (8x25)

Microplate Lid, black, sterile, with spacers for improved airflow. For stacker operation.
List Price : 333.00 USD
SureFire principle

AlphaScreen SureFire p70 S6K (p-Thr229) Assay Kit

The AlphaScreen® SureFire® p-p70 S6K (Thr229) assay is a sandwich immunoassay for quantitative detection of phospho-p70 S6K (phosphorylated on Thr229) in cellular lysates using Alpha Technology.
Price Range : 1493.00 USD - 16100.00 USD
Receptor-expressing cell lines

ValiScreen Cannabinoid CB1 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

FCGR3A/CD16A (176Phe/F158) (human) AlphaLISA Detection Kit

This kit is designed for the detection of binding activity between human FCGR3A (176Phe) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding.
Price Range : 583.00 USD - 10600.00 USD
AlphaLISA immunoassay kits

PSMA (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human PSMA enables the quantitative determination of human prostate specific membrane antigen (PSMA) in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 600.00 USD - 14400.00 USD
Receptor-expressing cell lines

Galanin Gal2 AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

Membrane Target Systems: Serotonin 5-HT1a (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Serotonin 5-HT1a receptor, in HEK-293 cells.
List Price : 936.00 USD

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