PerkinElmer

Fluorescent Agents, Labeling Kits & Dyes

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Our comprehensive suite of fluorescent dyes, agents, and labeling kits enable unmatched imaging of a broad range of disease-related biomarkers and pathways in your research models. Our fluorescent reagents and nanoparticles are optimized for use in the full range of optical in vivo imaging systems, as well as other fluorescence microscopy systems and many in vitro and cell-based systems.

The superior brightness and properties of our fluorescent dyes and labeling kits are ideal for labeling and imaging across a wide range of research areas. Most of our fluorescent dyes are available in both succinimide ester and maleimide chemistries for convenient labeling of proteins.

PerkinElmer’s comprehensive suite of fluorescent dyes, agents and labeling kit

  • Fluorescent agents – Targeted, Activatable, and Vascular fluorescent agents deliver imaging data on biological targets, pathways and processes in the context of the living system
  • Fluorescent dyes & labeling kits – available in several wavelengths, ideal for the labeling and imaging proteins, antibodies, and small molecules in a wide range of research areas
  • Fluorescent panels bundled by application

For research use only. Not for use in diagnostic procedures.

Products & Services (66)
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Therapeutic Area
  • Angiogenesis (9)
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  • Vascular disease (5)
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  • Fluorescence (65)

1-12 of 66 Products & Services

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  • In vivo Fluorescent Agents

    OsteoSense 800 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 607.00 USD
  • VivoTag Fluorochrome - 1 mg quantity

    VivoTag 680 XL Fluorochrome (1mg)

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
    List Price : 178.00 USD
  • In vivo Fluorescent Agents

    MMPSense Fluorescent Imaging Agent

    Matrix metalloproteinases (MMPs) are calcium-dependent zinc containing endopeptidases responsible for the degradation of most of extracellular matrix proteins during organogenesis, growth and normal tissue turnover. MMPs play a role in almost every biological cell process from embryo implantation to cell death and have been implicated in a wide range of diseases including inflammation, arthritis, pulmonary disease, cancer and more.

    PerkinElmer’s MMPSense NIR activatable fluorescence agents are designed to evaluate many disease related processes including cancer progression, rheumatoid arthritis, pulmonary disease and more as well as evaluating therapeutic efficacy of potential drug candidates.

    List Price : 731.00 USD
  • In vivo Fluorescent Agents

    IntegriSense 645 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 731.00 USD
  • VivoTrack-680 Fluorescent Labeling Kit - Standard Kit NEV12000

    VivoTrack 680 NIR Fluorescent Imaging Agent (Standard Kit)

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
    List Price : 273.00 USD
  • In vivo Fluorescent Agents

    AngioSense 680EX Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
    List Price : 601.00 USD
  • RediJect Probe Explorer Kit

    RediJect Bacterial Detection Fluorescent Imaging Probe (Explorer Kit)

    XenoLight RediJect Bacterial Detection Probe is a near-infrared (NIR) fluorescent agent for in vivo targeting of both Gram-positive and Gram-negative bacterial infections. 
    List Price : 154.00 USD
  • In vivo Fluorescent Agents

    AminoSPARK 680 NIR Fluorescent Nanoparticle

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 911.00 USD
  • In vivo Fluorescent Agents

    ProSense Fluorescent Imaging Agent

    Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time. PerkinElmer’s ProSense® imaging agents are protease activatable NIR fluorescent probes that are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation. ProSense is available in 3 formats; 680, 750 EX, and 750 FAST.
    Price Range : 601.00 USD - 710.00 USD
  • In vivo Fluorescent Agents

    BacteriSense 645 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.  
    List Price : 1047.00 USD
  • In vivo Fluorescent Agents

    IntegriSense 750 Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
    List Price : 717.00 USD
  • XenoLight DiR Fluorescent Dye

    XenoLight DiR Fluorescent Dye

    XenoLight DiR NIR Fluorescent Dye can be used for non-invasive imaging of T-cell or stem cell homing in vivo
    List Price : 169.00 USD
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  • Application Note

    NIR Fluorescent Cell Labeling for In Vivo Cell Tracking (VivoTrack 680)

    Fluorescent dyes have been used for many years to label cells for microscopy studies, and a variety of dyes in the visible fluorescence spectrum are available to label different cellular compartments and organelles. Efficient delivery of the fluorophore to the cell without excessively modifying surface proteins or perturbing cell function is the major biotechnological challenge. In addition, researchers have taken on the challenge of in vivo imaging, focusing on near infrared (NIR) dyes that fluoresce in a spectral region better suited for in vivo imaging due to reduced background and higher tissue penetration.

  • Application Note

    Vascular Imaging Probes For Oncology and Inflammation Using the IVIS Spectrum

    Optical-based in vivo imaging of vascular changes and vascular leak is an emerging modality for studying altered physiology in a variety of different cancers and inflammatory states. A number of fluorescent imaging probes that circulate with the blood, but have no target selectivity, have been used to detect tumor leakiness as an indication of abnormal tumor vasculature. Inflammation is also characterized by distinct vascular changes, including vasodilation and increased vascular permeability, which are induced by the actions of various inflammatory mediators. This process is essential for facilitating access for appropriate cells, cytokines, and other factors to tissue sites in need of healing or protection from infection. This application note investigates the use of three fluorescent imaging probes, to detect and monitor vascular leak and inflammation in preclinical mouse breast cancer models.

  • Application Note

    Imaging Hepatocellular Liver Injury using NIR-labeled Annexin V

    Drug induced liver injury (DILI) is a major reason for late stage termination of drug discovery research projects, highlighting the importance of early integration of liver safety assessment in the drug development process. A technical approach for in vivo toxicology determination was developed using Acetaminophen (APAP), a commonly used over-the-counter analgesic and antipyretic drug, to induce acute hepatocellular liver injury.

  • Application Note

    Multiplex 2D Imaging of NIR Molecular Imaging Agents on the IVIS SpectrumCT and FMT 4000

    Epifluorescence (2D) imaging of superficially implanted mouse tumor xenograft models offers a fast and simple method for assessing tumor progression or response to therapy. This approach for tumor assessment requires the use of near infrared (NIR) imaging agents specific for different aspects of tumor biology, and this Application Note highlights the ease and utility of multiplex NIR fluorescence imaging to characterize the complex biology within tumors growing in a living mouse.

  • Poster

    Combined efficacy & toxicity imaging following acute 5-FU treatment of HT-29 tumor xenografts

    Cancer chemotherapy can produce severe side effects such as suppression of immune function and damage to heart muscle, gastrointestinal tract, and liver. If serious enough, tissue injury can be a major reason for late stage termination of drug discovery research projects, so it is becoming more important to integrate safety/toxicology assessments earlier in the drug development process. There are a variety of traditional serum markers, tailored mechanistically to specific tissues, however there are no current non-invasive assessment tools that are capable of looking broadly at in situ biological changes in target and non-target tissue induced by chemical insult.