Concern is growing about the impact of microplastics on the marine and freshwater ecosystem, and in particular the effect on the food chain. In addition to leaching harmful additives, microplastics generate a surface biofilm that concentrates organic pollutants such as pesticides and attracts potentially harmful bacteria. This biota is consumed by marine organisms with potentially harmful consequences for the organisms themselves, the food chain, and human health. Issues such as how microplastics affect reproduction, growth, and productivity of bio-organisms, and how changes in immune response can lead to increased susceptibility to infection, are critically important, as they can lead to disruption in the food chain. In terms of physical harm, there is evidence of tiny particles penetrating into tissue, or into the brain, causing behavioral changes. Such research demands cellular imaging and assay technologies, gene sequencing, and proteomic tools.
Typical applications include:
For research use only. Not for use in diagnostic procedure.
NEXTflex® library preparation kits are designed to reduce bias and increase the sensitivity, flexibility, and speed of library prep for both Illumina® and Ion Torrent™ sequencing platforms. An extensive selection of NEXTflex single index and dual index barcoded adapters is available to meet your specific multiplexing needs. Automation protocols for the PerkinElmer® Sciclone® NGS Workstation are available for many of the NEXTflex library prep kits for labs requiring higher sample throughput, reduced hands-on time, greater reproducibility, or improved process control.
For research use only. Not for use with diagnostic procedures.
The Sciclone® G3 NGS and NGSx workstations area complete benchtop solution for the automated construction of up to or greater than 96 libraries per day.
Next generation sequencing (NGS) technologies are enabling science at unprecedented rates. As the cost of sequencing declines, throughput continues to increase and the number of applications for which sequencing data can be used is expanding. The Sciclone® G3 NGS and NGSx liquid handling workstation was designed for high throughput, walkaway NGS sample preparation. The deck design and intuitive interface virtually eliminate cross contamination and user error. These liquid handlers simplify the construction of up to or greater than 96 libraries per day.