PerkinElmer

Drug Discovery Reagents

Drug discovery starts with an understanding of the basics of diseases and disease pathways. Throughout the process of unraveling the complexity of disease pathways, identifying and characterizing targets, high throughput screening, and lead optimization PerkinElmer has the assays you can count on.

PerkinElmer's drug discovery reagents cover a wide array of applications ranging from immunoassays platforms and kinase assays to reporter gene, cytotoxicity and cell proliferation assays. Our easy-to-use platforms provide greater sensitivity, wide dynamic range, and reduced background.

From basic science to high throughput screening and lead optimization, PerkinElmer drug discovery reagents provide easy-to-use next generation assays every step of the way.



Explore Our Reagents By Assay Technology

Alpha

Alpha Technology

Alpha is a homogeneous, bead-based assay platform offering several advantages over traditional ELISAs. This versatile, easy-to-use platform is suitable for a wide range of applications.

AlphaLISA®, AlphaLISA SureFire® Ultra, Alpha Screen®, AlphaPlex®, and Alpha kits and standalone reagents can be used to detect:

  • Proteins and phosphoproteins
  • Protein: protein interactions – both high and low affinity
  • Receptor-ligand interactions
  • DNA interactions
  • Post-translational protein modifications

Learn More

TR-FRET

TR-FRET Technology

TR-FRET combines the benefits of Time Resolved Fluorescence (TRF) with those of Forster Resonance Energy Transfer (FRET). PerkinElmer offers two TR-FRET technologies - HTRF® (Homogeneous Time Resolved Technology) and LANCE® (Lanthanide Chelate Excite) Ultra TR-FRET.

HTRF and LANCE Ultra kits and standalone reagents can be used to detect:

  • Proteins and phosphoproteins
  • Protein: protein interactions
  • Receptor-ligand interactions
  • Second messenger levels

Learn More

TRF

TRF Technology

DELFIA® (Dissociation-Enhanced Lanthanide Fluorescence Immunoassay) is a washed based, time-resolved fluorescence (TRF) detection platform that utilizes fluorescent lanthanide chelates rather than other fluorophores. While superficially quite similar to an ELISA, DELFIA® comes with additional benefits. DELFIA® has a stable, time-resolved fluorescent signal which improves the assay dynamic range.

DELFIA® kits and standalone reagents can be used to detect:

  • Proteins and phosphoproteins
  • Protein: protein interactions
  • Cytotoxicity
  • Cell proliferation

Learn More

Luminescence

Luminescence Assays

Luminescence assays are used throughout the drug discovery workflow. Our assays are provided a simple, easy-to-use microplate format.

Our luminescence assays include:

  • Reporter gene assays
  • Cytotoxicity and cell proliferation assays
  • Kinase activity assays

Learn More

Receptor Cell Lines & Membranes

Receptor Cell Lines & Membranes

Whether you are working with cell-based or biochemical assays, our GPCR overexpressing cell lines and membranes originate from clones carefully selected to produce the most effective assays.

Our cell line clones have been selected to produce the most effective:

  • Radioligand binding
  • GTP binding
  • cAMP activation
  • Calcium flux
  • Downstream phosphorylation measurements

Learn More

Radiometric

Radiometric Assays

Radiometric detection remains the most sensitive assay today. We offer scintillation proximity assays (SPAs) and radiolabeled ligands for ligand binding studies, plus a vast array of radiochemicals for all your research needs.

Our products support a range of radiometric assays, including:

  • Scintillation Proximity Assays (SPA)
  • Receptor-Ligand binding assays – using either tritiated and iodinated compounds

Newest Assays

PerkinElmer R&D scientists focus on developing fully validated, ready-to-use kits and reagents for the hottest new targets. We continue to evolve our product offering as your science evolves.

Our Alpha, HTRF®, LANCE® Ultra TR-FRET, and DELFIA® TRF technologies offer alternatives to standard ELISA assays, each with a larger dynamic range and higher signal-to-noise ratio. Alpha, HTRF and LANCE Ultra TR-FRET have the added advantage of having no wash or separation steps, saving you valuable time.

Learn More

Immunoassays

PerkinElmer offers a range of ELISA alternative immunoassay technologies that enable selection of the optimal immunoassay platform for your requirements. From sample compatibility to sample volume, throughput, detectable range, signal window, signal stability, reproducibility, automation compatibility, and desired speed of results, PerkinElmer offers immunoassay technology platforms, pre-configured kits, and customizable reagents for superior results.

Learn More

Microplates

Better Microplates Means Better Results

A microplate is a critical part of your discovery process. Microplates have the capability to generate valuable, information-rich data that bring great insights into discovery screening.

Microplate planarity and inaccurate data collection are common issues caused by microplates that are not carefully designed for the unique challenges of sample screening which can result in missed data points, sample re-screening, missed project timelines, and ultimately higher costs.

Learn More

Microplate Readers

PerkinElmer offers a family of plate readers focused on performance, versatility, and reliability for today's laboratory needs. Our drug discovery reagents are validated using our microplate readers, ensuring optimal performance when used together.

Learn More

OnPoint Custom Solutions

Are you working on a novel target? Need to develop an assay? We’re here to help. Choose between custom labeling or custom assay development. Let our experts

  • Extend your lab's capabilities by labeling your sample so you can develop your own assay – Alpha, HTRF, LANCE Ultra and DELFIA labeling available.
  • Let us develop an assay to your specifications.

Learn More

Explore Our Reagents By Target Area

Biomarker Detection Reagents

Our biomarker detection reagents and kits are designed to excel in applications that rely on high sensitivity, wide dynamic range, and easy automation. With no ...

Learn More

Protein-Protein Interaction Research Reagents

The interactions and binding of proteins are implicated in a large number of biological processes. The need for efficient, highly sensitive assays to study larg ...

Learn More

Protein Kinase Research Reagents

Cancer, diabetes, and Alzheimer’s research can benefit from the study of phosphorylation and protein kinase activity. Because of their role in signal transducti ...

Learn More

GPCR Research Reagents

GPCR research remains a widely studied area in drug discovery. As the complexity of the roles of GPCRs in signaling are unraveled, it is as important as ever to ...

Learn More

Epigenetic Research Reagents

As the understanding of the role of epigenetic changes in various disease states advances, the need for high quality reagents that can rapidly identify and vali ...

Learn More

Cytokine Research Reagents

Cytokines regulate several physiological and pathological roles including innate immunity, acquired immunity, and many inflammatory responses. PerkinElmer offer ...

Learn More

Explore Our Reagents By Therapeutic Area

Immuno-oncology Reagents

Immuno-oncology (I-O) is a rapidly expanding area of personalized medicine. Researchers are exploring the complex relationship between tumor cells and the immun ...

Learn More

Neuroscience Research

Many prominent scientists, philosophers, and artists alike are mesmerized by the brain, likening this 3 lbs of matter to a computer, a great factory, a beautifu ...

Learn More

Cardiovascular Disease Research

Cardiovascular disease is a leading cause of death globally, and understanding its causes is critical for treatment and preventative care. Our phenotypic and ta ...

Learn More

Metabolic Disease

Metabolic disorders occur when the body's usual metabolic processes are disrupted - numerous molecular pathways and thus, several organs, can be affected. These ...

Learn More

Virology Reagents

Viruses and virally transmitted diseases have been impacting human health and well-being for millennia. Some of our greatest scientific challenges and medical t ...

Learn More

Want to learn more about our drug discovery reagents?