PerkinElmer

Cell-Based Solutions for Cancer Research

Cell-based assays are a proven and powerful tool for gaining a more complete understanding of cancer biology, providing more meaningful results in more physiologically relevant systems than classical biochemical assays - instrumental in streamlining cancer research and drug discovery.

Whether you are a basic researcher trying to better understand biological processes in cancer cells or investigating how drugs affect those processes, we have the tools you need to advance your cancer research and discovery.

Our cell-based cancer research solutions allow you to:

  • Gain deeper insights from phenotypic screening of live cancer cells, 3D cell models, and stem cells with our high content screening and informatics solutions
  • Monitor the health of cells with luminescence assays
  • Study the mechanisms of metal-based chemotherapy resistance in single cells using our innovative SC-ICP-MS system
  • Compliment traditional histochemistry techniques using IR spectroscopy to evaluate features of the tumor microenvironment

For research purposes only. Not for use in diagnostic procedures.

Applications & Techniques

High-Content Analysis

Cell imaging has revolutionized cancer biology by enabling cells to be seen more clearly and in more detail.

Take your cell imaging to the next level with high-content analysis:

  • Gain more information from cellular samples and complex 3D cell models
  • Create meaningful functional screening assays for the development of drugs which prevent tumor growth and metastasis
  • Answer more questions simultaneously with multi-parametric data sets that are more information-rich compared to non-imaging read-outs

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Cytotoxicity & Cell Proliferation Assays

Cytotoxicity and cell proliferation assays are widely used in cancer research and drug discovery providing valuable insights to the health of cells.

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Single Cell ICP-MS for Cancer Research

Study the mechanisms of metal-based chemotherapy at the cellular level in individual cancer cells using Single Cell ICP-MS.

  • Gain a better understanding of how cancer cells become resistant to metal-based chemotherapy
  • Study and quantify uptake of metal-based nanoparticles in single cells for targeted cancer therapy
  • Evaluate effects of potentially new metal-based therapies

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Tumor Microenvironment

Identify chemical and morphologic features of the tumor microenvironment using Fourier transform infrared (FT-IR) spectroscopic imaging.

  • Innovative stain-free approach to compliment traditional histochemistry techniques
  • Differentiate molecular differences between normal and diseased tissues
  • Research transition of normal cells into cancerous cells in the tumor microenvironment

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Featured Products

NexION 2000 B ICP Mass Spectrometer

PerkinElmer’s NexION® 2000 is the most versatile ICP-MS on the market, featuring an array of unique technologies that combine to deliver the highest performance no matter what your analytical challenge. Discover the effortless versatility of an instrument that makes it easy to handle any sample matrix, any interference, and any particle size.

PerkinElmer received on April 11, 2018 the Application Award from LaborPraxis in the category Bio and Pharma Analysis for the NexION 2000 ICP-MS. We were awarded this prize during analytica 2018 in Munich, Germany, in acknowledgment of a new technique enabling users to quantify the amount of metal in an individual cell for the first time.

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Opera Phenix High-Content Screening System

The Opera Phenix High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.

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VICTOR Nivo Multimode Microplate Reader

Building on our family of benchtop multimode plate readers, the VICTOR Nivo system packs all popular detection modes into the industry’s smallest multimode reader footprint. The perfect microplate reader for everyday biochemical and cell-based assays, it measures at any wavelength, with top and bottom reading of all technologies. Its software interface is easy to learn and use, and lets you control the instrument from almost any device – perfect for multiuser environments. Combine with our assays and reagents to get you started right away.

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Operetta CLS High-Content Analysis System

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.

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Spotlight 400 FT-IR Imaging System

Spotlight IR microscope systems are designed to meet the challenges of an expanding laboratory by generating high-quality, reproducible data from a variety of sample types. The Spotlight 400 FT-IR Imaging System combines high sensitivity and rapid imaging with ease-of-use. The ability to image large sample areas rapidly at high spatial resolution extends FT-IR microscopy into new applications.

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ATPlite Luminescence Assay System, 300 Assay Kit

ATP-monitoring luminescence assay for quantitative evaluation of proliferation and cytotoxicity of cultured mammalian cells.

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DELFIA® EuTDA Cytotoxicity Reagents

DELFIA® TRF (time-resolved fluorescence) cytotoxicity kit for measuring chemical cytotoxicity, cell-mediated cytotoxicity, and ADCC.

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DELFIA®Cell proliferation kit, 10 x 96 wells

DELFIA® time-resolved fluorescence (TRF) cell proliferation kit for measuring cytotoxicity or proliferation in mammalian cells.

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Contact us to see how we can help you with your next cancer breakthrough